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Professor Dr. Erich Gulbins

Address Universitätsklinikum Essen
Institut für Molekularbiologie
Hufelandstraße 55
45147 Essen

Projects

As Applicant
- Current projects
  - Molecular mechanisms of sphingosine-mediated killing of bacteria (Research Grants)
  - Role of the acid ceramidase and sphingosine for the interplay of viral and bacterial pulmonary infections (Research Grants)
  - Inhibition of SARS-CoV-2 infections of human lungs by functional inhibitors of the acid sphingomyelinase (Research Grants)
  - Mechanisms and personalized treatment of depression-induced alcoholism (Research Grants)
- Completed projects
  - Molekulare Mechanismen der Aktivierung von T-Lymphozyten über den CD40-Liganden (Research Grants)
  - Sphingolipide und bakterielle Infektionen (Research Grants)
  - Rolle der sauren Sphingomyelinase in Thrombozyten bei der Tumormetastasierung (Research Grants)
  - Regulation of cell death by interaction of Bax with mitochondrial Kv1.3 (Research Grants)
  - The acid sphingomyelinase/ceramide-hypothesis of major depression (Research Grants)
  - Experimentelle Tumortherapie durch Ceramid-vermittelte Amplifikation von Todesrezeptoren (Research Grants)
  - Regulation of pulmonary inflammation in cystic fibrosis by ceramide (Priority Programmes)
  - Coordination project: Sphingolipids - Signals and Disease (Priority Programmes)
  - The acid sphingomyelinase/ceramide hypothesis of major depression (Priority Programmes)
  - Regulation of hematogenous ans lymph node tumor metastisis by acid sphingomyelinase (Research Grants)
  - Role of the acid sphingomyelinase/ceramide system in lung edema induced by Staphylococcus aureus toxin (Research Units)
  - Coating of endotracheal tubes with sphingosine to prevent bacterial growth and ventilator-associated pneumonia (Research Units)
  - Role of neutral sphingomyelinase in mycobacterial infections (Research Units)
  - Mechanisms and personalized treatment of depression-induced alcoholism (Research Grants)
  - Regulation of the effects of antidepressants by sphingomyelin- and ceramide-controlled autophagy (Research Grants)
  - Sphingosine inhalation as a novel treatment for bacterial pneumonia (Research Grants)
As Leader
- Completed projects
  - Konfokales Laserscanning Mikroskop (Major Research Instrumentation)
As Spokesperson
- Completed projects
  - SPP 1267: Sphingolipids - Signals and Disease (Priority Programmes)
  - GRK 2098: Biomedicine of the acid sphingomyelinase/acid ceramidase system (Research Training Groups)
As Participating Researcher
- Completed projects
  - GRK 1045: Modulation of Host Cell Functions to Treat Viral and Bacterial Infections (Research Training Groups)
  - GRK 1739: Molecular Determinants of the Cellular Radiation Response and their Potential for Response Modulation (Research Training Groups)
As Participating Person
- Completed projects
  - Gfi1 in innate immunity: a downstream effector of Toll like receptor signaling and a novel regulator of endotoxin tolerance (Priority Programmes)
  - Central service project - Analysis and Synthesis of sphingolipids (Priority Programmes)

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