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Universitätsklinikum Aachen, AÖR
Klinik für Nieren- und Hochdruckkrankheiten, Rheumatologische und
Immunologische Erkrankungen (Medizinische Klinik II)

Address Pauwelsstraße 30
52074 Aachen
Deutschland

GERiT This institution in GERiT

52074 Aachen

Projects

Research Fellowships
- Completed projects
Priority Programmes
- Completed projects
  - Molekulare Mechanismen der chronischen Glomerulonephritis - Funktion eines neuen kleinen Heparansulfat-Proteoglycans in der glomerulären Basalmembran (Molecular basis of renal disease - function of a novel small heparan sulfate proteoglycan in the glomerular basement membrane)
    (Applicant Floege, Jürgen )
Research Grants
- Current projects
- Completed projects
Research Units
- Completed projects
  - Die Bedeutung von FAT1 für die Ausbildung der Fußfortsätze und Schlitzmembran in Podozyten
    (Applicant Möller, Marcus )
Heisenberg Professorships
- Completed projects
  - Preventive Nephrology
    (Applicant Möller, Marcus )
Heisenberg Grants
- Completed projects
  - Preventive and translational nephrology
    (Applicant Möller, Marcus )
Independent Junior Research Groups
- Current projects
  - Using spatially resolved functional genomics to dissect mechanisms of chronic kidney disease and identify novel therapeutic targets
    (Applicant Kuppe, Christoph )
Collaborative Research Centres
- Completed projects
  - Central Services of the Collaborative Research Program
    (Project Heads Floege, Jürgen ; Müller-Newen, Gerhard )
  - CXCR and CD74 receptor mechanisms of the cytokine MIF and their role in nephrotoxic nephritis
    (Project Heads Bernhagen, Jürgen ; Ostendorf, Tammo ; Weber, Christian )
  - Die Rolle von Endothel und Hypertonus in der chronischen Nierentransplantat-Dysfunktion
    (Project Heads Brunkhorst, Reinhard ; Floege, Jürgen ; Nashan, Björn )
  - Interventions in the PDGF system: A new therapy approach in inflammatory renal disease
    (Project Heads Floege, Jürgen ; Ostendorf, Tammo )
  - SFB 542: Molecular Mechanisms of Cytokine-Mediated Inflammatory Processes: Signal Transduction and Pathophysiological Consequences
    (Spokesperson Floege, Jürgen )
CRC/Transregios
- Current projects
  - PDGFR-Signalisierung bei CVD in CKD
    (Project Heads Boor, Ph.D., Peter ; Floege, Jürgen )
  - Vitamin-K-abhängige Mechanismen der kardiovaskulären Verkalkung bei CKD
    (Project Heads Floege, Jürgen ; Kaesler, Nadine ; Kramann, Rafael )
- Completed projects
  - Cell-specific role of the PDGF system in renal fibrosis
    (Project Heads Boor, Ph.D., Peter ; Floege, Jürgen )
  - Mesenchymal stem cells in renal fibrosis: benefits and risks
    (Project Heads Floege, Jürgen ; Kunter, Uta )
  - Molecular mechanisms of renal fibrosis: analysis of the pathophysiological role of Platelet Derived Growth Factor-C (PDGF-C)
    (Project Heads Eitner, Frank ; Ostendorf, Tammo )
  - Parietal epithelial cell activation and glomerulosclerosis: Mechanisms, mediators and clinical diagnosis
    (Project Heads Möller, Marcus ; Ostendorf, Tammo )
Clinical Research Units
- Current projects
  - Altered cellular compartmentalization as a potential pathomechanism driving CKD.
    (Applicants Antonin, Wolfram ; Möller, Marcus )
  - Coordination Funds
    (Applicant Boor, Ph.D., Peter )
  - Dissecting IgA nephropathy via integration of multi-omics data
    (Applicants Saez-Rodriguez, Julio ; Seikrit, Claudia )
  - Dissecting regulatory programs of kidney disease transition using functional genomics
    (Applicants Gesteira Costa Filho, Ivan ; Kuppe, Christoph )
  - KFO 5011: Integrating emerging methods to advance translational kidney research (InteraKD)
    (Spokesperson Boor, Ph.D., Peter )
  - Modulation of tubular cell transition to a regenerative phenotype in AKI - diagnostic and therapeutic implications
    (Applicants Jankowski, Vera ; Stamellou, Ph.D., Eleni )
International Research Training Groups
- Completed projects
  - GRK 1508: Arterial Remodelling
    (Spokesperson Bernhagen, Jürgen )

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