Project Details

Professor Dr. Detlef Schuppan

Address Johannes Gutenberg-Universität Mainz
Universitätsmedizin Mainz
Institut für Translationale Immunolgie (TIM)
Langenbeckstraße 1
55131 Mainz

Projects

As Applicant
- Current projects
  - Active celiac disease as promoter of cardiovascular morbidity: exploration of underlying mechanisms and effect of therapeutic intervention (Research Grants)
- Completed projects
As Participating Researcher
- Completed projects
  - GRK 750: Vascular Injury in Heart and Kidney: Pathogenesis and Diagnostics (Research Training Groups)
As Project Head
- Current projects
  - Therapy of primary and secondary liver tumors by addressing tolerance-inducing M2 macrophages using immunomodulating nanoparticles (Collaborative Research Centres)
  - Modulating macrophages and platelets in hepatocellular carcinoma and infection (Collaborative Research Centres)
  - Treg cells as modulators of gluten-induced inflammation in celiac disease (CRC/Transregios)
  - Iron regulation and oxidative stress in systemic sclerosis (CRC/Transregios)
- Completed projects
  - Signalübertragung durch Matrix (Collaborative Research Centres)
  - Einfluss von CTGF und Endostation auf die renale Angiogenese und Fibroplasie (Collaborative Research Centres)
  - Impact of diet and intestinal microbiota on the gut-CNS-axis – implications for CNS autoimmunity (CRC/Transregios)
As Ehemaliger Antragsteller
- Completed projects
  - Modulation der Verfügbarkeit und Aktivität von Matrix-Metalloproteinasen durch (synthetische) Matrixpeptide (Research Grants) to 5/2005
  - Development of antifibrotic therapies for chronic liver diseases (Research Grants) to 5/2005
  - Rolle der Transglutaminase (tTG) und tTG-spezifischer Antikörper in Pathogenese und Diagnostik der Zöliakie/Sprue und anderer Autoimmunerkrankungen (Research Grants) to 12/2005
As Host
- Completed projects
  - Charakterisierung der Mechanismen einer Gliadin-Peptid-vermittelten angeborenen Immunreaktion bei Zöliakie (Research Fellowships)
As Co-Applicant
- Completed projects
  - Inhibition of angiogenesis by gene therapeutic expression of endostatin as a molecular therapy for hepatocellular carcinoma (HCC) (Research Grants)

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Professor Dr. Detlef Schuppan

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Detlef Schuppan

Additional Information

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