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Professor Dr. Chris Meier

Address Universität Hamburg
Fachbereich Chemie
Institut für Organische Chemie
Martin-Luther-King-Platz 6
20146 Hamburg

Projects

As Applicant
- Completed projects
  - Synthesis and antiviral activity of pronucleotides on the basis of cyclic phosphate triesters (Research Grants)
  - Diastereoselektive Synthese und Eigenschaften von fluoreszierenden cycloSal-Phosphattriestern (Research Grants)
  - Synthesis of Arylamin-modified DNA-oligonucleotides - why are monocyclic aromatic Amins less mutagenic/carcinogenic than polycyclic aromatic Amins? (Research Grants)
  - Diastereoselektive Synthese von cycloSal- und anderen Pronucleotiden (Research Grants)
  - Synthese von enzymatisch-aktivierbaren "lock-in"-Pronucleotiden antiviral aktiver Nucleosid-Analoga (Research Grants)
  - Entwicklung bioreversibel geschützter Nucleosiddi- und Nucleosidtriphosphate als potentielle Prodrugs in der antiviralen Therapie (Research Grants)
  - Diastereomerenreine Pronucleotide von potenteill anti-Hepatitis C aktiven carbocylischen Nucleosid-Analoga (Research Grants)
  - gamma-modified triphosphates of nucleoside analogues as potential antivirals and lipophilic prodrugs therof (Research Grants)
  - Development of antitumor-active Nucleoside Triphosphate Prodrugs (Research Grants)
  - INtraCELLular delivery of PHOSphorylated tools to TAG proteins using next generation nucleoside triphosphate derivatives (Research Grants)
As Participating Researcher
- Completed projects
  - GRK 464: Glycoconjugates: Synthesis, Analysis, Structure and Function (Research Training Groups)
As Project Head
- Current projects
  - Synthesis of membrane-permeable, bioreversible-protected second messenger and ATP-selective fluorescent chemosensors (Collaborative Research Centres)
  - Targeting the ADPR-binding macrodomain associated deMARylation/dePARylation enzyme activity as novel approach towards SARS-CoV-2 (Collaborative Research Centres)
  - Determinants of heterospecific phase separation in negative-strand RNA viruses (Collaborative Research Centres)
  - Characterization of host factors as targets for the development of broadly acting therapeutics against emerging viruses (Collaborative Research Centres)
- Completed projects
  - Synthese von Nucleosiddiphosphat-Pyranosen mit Hilfe von cycloSal-aktivierten Phosphat-Donatoren und Entwicklung von Prodsugs phosphorylierter Zucker-Derivate (Collaborative Research Centres)

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