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Institution
Julius-Maximilians-Universität Würzburg
Biozentrum der Universität Würzburg
Lehrstuhl für Zell- und Entwicklungsbiologie (Zoologie I)
Address
Am Hubland
97074 Würzburg
Deutschland
GERiT
This institution in GERiT
97074 Würzburg
Projects
Research Grants
Current projects
An in silico model of the African trypanosome: Moving in complex environments
(Applicant
Stark, Holger
)
Do trypanosomes control mRNA export?
(Applicant
Kramer, Susanne
)
Mapping mRNP-NUP interactions during nuclear export with a unique mRNA-trap
(Applicant
Kramer, Susanne
)
Targeting a unique mRNA decapping enzyme for trypanosomatid infectious disease drug discovery, chemical biology and biotechnology applications
(Applicant
Kramer, Susanne
)
Completed projects
Antibody clearance and trans-sialylation as virulence factors in African trypanosomiasis
(Applicant
Engstler, Markus
)
Antibody clearance as virulance factor in African sleeping sickness
(Applicant
Engstler, Markus
)
Comparative analyses of the function of the neuropeptide corazonin in three insect species and a nematode
(Applicant
Scheller, Klaus
)
Exploring the regulation of trypanosome RNA granules with a newly established RNA granule purification protocol.
(Applicant
Kramer, Susanne
)
Funktionelle Architektur des Synaptonemalen Komplexes
(Applicant
Benavente, Ricardo
)
Germ cell-specific LINC complexes and their relevance for nuclear remodelling, shaping and fertility
(Applicant
Alsheimer, Manfred
)
Impact of telomere-associated protein complexes on VSG expression site regulation and structure in Trypanosoma brucei
(Applicants
Butter, Falk
;
Janzen, Christian
)
In vivo Interaktion von Proteinen der Kernhülle
(Applicant
Krohne, Georg
)
Membrane Biophysics of African Trypanosomes
(Applicant
Engstler, Markus
)
molecular analysis of rapid endocytosis and plasma membrane recycling in the model eukaryote Trypanosoma brucei
(Applicant
Engstler, Markus
)
Molecular Architecture of Meiotic Chromosomes
(Applicant
Benavente, Ricardo
)
mRNA decapping by ApaH like phosphatases
(Applicant
Kramer, Susanne
)
Properties and function of gametogenesis specific nuclear lamins
(Applicant
Alsheimer, Manfred
)
Regulation of antigenic variation by a DOT1B/RNaseH2 complex in Trypanosoma brucei
(Applicant
Janzen, Christian
)
Role of HMGA1a and ORC interaction in origin definition and heterochromatin organization
(Applicant
Hock, Robert
)
Rolle der chromosomalen Nicht-Histon-Proteine HMG14 und HMG17 bei zellulären Differenzierungsprozessen und embryonalen Entwicklungsvorgängen
(Applicant
Hock, Robert
)
The function of histone H3 lysine 76 methylation in host-induced differentiation in Trypanosoma brucei
(Applicant
Janzen, Christian
)
Unraveling the mechanism of DOT1A-mediated replication regulation in Trypanosoma brucei
(Applicant
Janzen, Christian
)
Priority Programmes
Current projects
Coordination Funds
(Applicant
Engstler, Markus
)
Mechanical strategies to avoid interspecies competition in trypanosomes
(Applicant
Engstler, Markus
)
SPP 2332: Physics of Parasitism
(Spokesperson
Engstler, Markus
)
Completed projects
Architektur der Kernperipherie meiotischer Zellen
(Applicant
Benavente, Ricardo
)
From solitary swimmers to swarms and back: trypanosomes on their journey through the tsetse fly
(Applicant
Engstler, Markus
)
Hydrodynamic flow-induced protein movement on cell surfaces: African trypanosomes as model
(Applicants
Engstler, Markus
;
Pfohl, Thomas
)
Insertion of nuclear pore complexes into the nuclear membrane
(Applicant
Dabauvalle, Marie-Christine
)
In vivo Interaktion von Proteinen der Kernhülle In vivo interactions of nuclear envelope proteins
(Applicant
Krohne, Georg
)
Molecular architecture, dynamics and evolution of the synaptonemal complex
(Applicant
Benavente, Ricardo
)
Molecular requirements for nuclear envelope attachment and movements of meiotic telomeres
(Applicant
Alsheimer, Manfred
)
Nuclear export of proteins with leucine-rich nuclear export signals (NES) in vivo and in vitro
(Applicant
Dabauvalle, Marie-Christine
)
Proteinverkehr und Kontrolle der VSG-Sekretion bei Trypanosoma brucei
(Applicant
Engstler, Markus
)
Research Fellowships
Completed projects
Characterization of LEM-domain Proteins in Drosophila melanogaster and their relevance regarding human laminopathic diseases
(Applicant
Wagner, Nicole
)
Identifizierung und Charakterisierung von telomerbindenden Proteinen in Trypanosoma brucei
(Applicant
Janzen, Christian
)
Heisenberg Grants
Completed projects
Spatial regulation of mRNA metabolism in trypanosomes
(Applicant
Kramer, Susanne
)
CRC/Transregios
Completed projects
Mechanism of cell cycle tegulation by histone H3 lysine 76 methylation in Trypanosoma brucei
(Project Head
Janzen, Christian
)
Collaborative Research Centres
Completed projects
VSG as unexpected drug target for sleeping sickness
(Project Head
Engstler, Markus
)
Zellkultur- und Tiermodelle zur Aufklärung der gewebsspezifischen Pathogenese der Emery-Dreifuss Muskeldystrophie
(Project Heads
Dabauvalle, Marie-Christine
;
Müller-Reible, Clemens Rainer
)
Major Research Instrumentation
Completed projects
Hochauflösendes Feldemissions-Rasterelektronenmikroskop
Hochauflösendes Transmissionselektronenmikroskop
Research Training Groups
Current projects
GRK 2157: 3D Tissue Models for Studying Microbial Infections by Human Pathogens
(Spokesperson
Rudel, Thomas
)
Completed projects
GRK 639: The Molecular and Structural Basis of Tumorinstability
(Spokespersons
Gessler, Manfred
;
Müller-Hermelink, Hans-Konrad
)
GRK 1048: Molecular Basis of Organ Development in Vertebrates
(Spokesperson
Schartl, Ph.D., Manfred
)
GRK 1114: Optical Techniques for Measurement of Interfacial Transport Phenomena
(Spokesperson
Tropea, Cameron
)
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