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Institution
Universitätsklinikum Jena
Institut für Humangenetik
Address
Am Klinikum 1
07747 Jena
Deutschland
GERiT
This institution in GERiT
07747 Jena
Projects
Research Grants
Current projects
Anaylsis of the pathophysiology of GMPPA- and GMPPB-associated diseases
(Applicants
Blanchard, Ph.D., Véronique
;
Hübner, Christian Andreas
)
Pathophysiology of an autosomal recessive neurodevelopmental disorder caused by SLC4A10 loss-of-function
(Applicant
Hübner, Christian Andreas
)
Pyroptotic cell death in excessively stressed human periodontal ligament cells - a potential mechanism for hyperinflammatory responses?
(Applicant
Jacobs, Collin
)
Studying the pathophysiology of REEP1 and REEP2-associated axonal disorders
(Applicant
Hübner, Christian Andreas
)
Completed projects
Funktionelle Analyse der neuronalen Anionenaustauscher mit Hilfe von transgenen Mausmodellen
(Applicants
Dityatev, Ph.D., Alexander
;
Hübner, Christian Andreas
)
Gen-Umwelt-Interaktionen durch Wasserproben aus der WISMUT-Region an Humanzellen
(Applicant
Pool-Zobel, Beatrice L.
)
Grundlegende Studie zur chromosomalen Architektur: Biologische Hierarchie der Aufspaltung der humanen chromosomalen Banden
(Applicant
Liehr, Thomas
)
Impaired organelle turnover in the FAM134B-mediated neuropathy
(Applicants
Hübner, Christian Andreas
;
Kurth, Ingo
)
Ionentransporter und GABAerge Transmission
(Applicants
Hübner, Christian Andreas
;
Jentsch, Thomas J.
)
Multicolor-banding (mcb) für die Maus (Mus musculus) sowie Charakterisierung der Mauszelllinie WMP 2 und zweier Nagerspezies
(Applicant
Liehr, Thomas
)
Pathophysiology of adaptor protein 5 complex related hereditary spastic paraplegia
(Applicant
Hübner, Christian Andreas
)
Pathophysiology of distal renal tubular acidosis
(Applicant
Hübner, Christian Andreas
)
Role of Sas-4 in centrosome maturation
(Applicant
Gopalakrishnan, Ph.D., Jay
)
Signaltransduktion und Mechanismen der Corepressor-Kernhormonrezeptor Dissoziation
(Applicant
Baniahmad, Aria
)
The role of DNA-Methyltransferase1 in cortical GABAergic interneuron differentiation, development and function
(Applicant
Zimmer-Bensch, Geraldine
)
Transgene Mausmodelle für die hereditäre spastische Paraplegie Typ 31 und axonale Degeneration
(Applicant
Deufel, Thomas
)
Untersuchung der physiologischen Rolle der K-CI-Kotransporter mit transgenen Mausmodellen
(Applicant
Jentsch, Thomas J.
)
Research Units
Current projects
Coordination Funds
(Applicant
Gopalakrishnan, Ph.D., Jay
)
FOR 2625: Mechanisms of Lysosomal Homeostasis
(Spokesperson
Braulke, Thomas
)
FOR 5547: Dissecting primary cilia dynamics in tissue organization and function
(Spokesperson
Gopalakrishnan, Ph.D., Jay
)
Primary cilia dynamics in determining neural progenitor cell maintenance in brain development
(Applicant
Gopalakrishnan, Ph.D., Jay
)
The role of AP-5 in the endolysosomal system, autophagy and autophagic lysosome reformation
(Applicant
Hübner, Christian Andreas
)
Completed projects
Role of AE3 and NHE1 in cardiomyocyte homeostasis and remodeling
(Applicant
Hübner, Christian Andreas
)
Thyroid Hormone Receptor Corepressors: Requirements and Selectivity for Histone Modifications Cell Culture
(Applicant
Baniahmad, Aria
)
Collaborative Research Centres
Completed projects
Entwicklungsbiologische und transkriptionelle Charakterisierung des Corepressors Alien in Drosophila und Säugern
(Project Heads
Baniahmad, Aria
;
Paululat, Achim
)
Funktionelle Analyse von Chlorid-Bikarbonat-Transportern mit transgenen Mausmodellen
(Project Head
Hübner, Christian Andreas
)
Transkriptionelle Charakterisierung des Coreprosessor Alien in Vertrebraten
(Project Head
Baniahmad, Aria
)
Research Fellowships
Completed projects
Charakterisierung kleiner überzähliger Markerchromosomen mittels Array-CGH
(Applicant
Weise, Anja
)
Priority Programmes
Completed projects
Developmental significance of GABAergic depolarization for the functional maturation of the primary visual cortex
(Applicants
Holthoff, Knut
;
Hübner, Christian Andreas
;
Kiebel, Stefan
;
Kirmse, Knut
)
Modeling of early-onset retinal dystrophy development in optic vesicle containing-brain organoids
(Applicants
Gopalakrishnan, Ph.D., Jay
;
Nagel-Wolfrum, Kerstin
)
Research Training Groups
Current projects
GRK 2155: ProMoAge - Protein Modification: A Key Mechanism for Ageing
(Spokesperson
Simm, Andreas
)
Completed projects
GRK 370: Biochemistry of Nucloeprotein Complexes
(Spokesperson
Pingoud, Alfred
)
GRK 533: Cell-Cell Interaction in Reproduction
(Spokesperson
Hinsch, Elvira
)
GRK 1715: Molecular Signatures of Adaptive Stress Responses
(Spokespersons
Heinzel, Thorsten
;
Wetzker, Reinhard
)
Additional Information
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