Medial temporal lobe and prefrontal cortex connectivity as a neural resource for recognition memory (B01#)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells ; Human Cognitive and Systems Neuroscience
• Term: from 2021 to 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 425899996

We hypothesise that neuronal ensembles’ size and local connectivity within hippocapus and prefrontal cortex subareas play an important role as a neural resource for recognition memory, but that these resources requires the engagement of both, hippocampus and prefrontal cortex circuitry, to be fully mobilised. Our research strategy capitalises on differences in animals between high and low performers by investigating how they correlate with the size of the neuronal ensembles in each subareas and with synaptic connectivity at the local and medial temporal lobe and prefrontal cortex network levels during recognition memory.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1436: Neural resources of cognition
• Applicant Institution: Otto-von-Guericke-Universität Magdeburg
• Project Heads: Matthias Prigge, Ph.D.; Professorin Dr. Magdalena Sauvage