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Project Details

Institution

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Ruprecht-Karls-Universität Heidelberg
Medizinische Fakultät Mannheim
European Center for Angioscience (ECAS)

Address Ludolf-Krehl-Straße 13-17
68167 Mannheim
Deutschland

GERiT This institution in GERiT

68167 Mannheim

Projects

Priority Programmes
- Completed projects
  - Analysis of lymphangiogenesis during tumorigenesis, wound healing, lymphedema and filariasis
    (Applicant Sleeman, Jonathan Paul )
  - Lymphangiogenesis and cancer
    (Applicant Sleeman, Jonathan Paul )
Research Grants
- Current projects
- Completed projects
Research Fellowships
- Completed projects
  - Bedeutung der Transokriptionsfaktoren GATA-4 und GATA-6 für Struktur, Funktion und Hypertrophieentwicklung des adulten Myokards in vivo
    (Applicant Heineke, Jörg )
Independent Junior Research Groups
- Current projects
  - Elucidating the regulatory mechanisms of mammalian cardiomyocyte cytokinesis to promote heart regeneration
    (Applicant Wu, Ph.D., Chi Chung )
- Completed projects
  - The role of Isl1-mediated transcriptional regulation and asymmetric cell division in fate decisions of cardiac progenitor cells
    (Applicant Dobreva, Gergana )
Clinical Research Units
- Completed projects
  - Bedeutung des Kapillarendothels für die myokardiale Adaption: Transkriptionelle Regualtionsmechanismen und Identifizierung kardioprotektiver Faktoren
    (Applicant Heineke, Jörg )
  - Human iPS cell based myocardial tissue as model of heart failure and cardiac assist device therapy: molecular characterization and identification of therapeutic strategies
    (Applicants Gruh, Ina ; Heineke, Jörg )
Heisenberg Fellowships
- Completed projects
  - Venia legendi Molekulare Kardiologie
    (Applicant Heineke, Jörg )
Heisenberg Professorships
- Completed projects
  - Molecular Mechanisms of Chronic Heart Failure
    (Applicant Heineke, Jörg )
Heisenberg Grants
- Current projects
  - Lymphatic endothelial cells as regulators of adaptive immunity and new targets for immunotherapy
    (Applicant Dieterich, Ph.D., Lothar )
CRC/Transregios
- Completed projects
  - Interaction of Platelets with Progenitor Cells: Implications for the Pathogenesis of Inflammatory Cardiomyopathy
    (Project Heads Gawaz, Meinrad Paul ; Stellos, Konstantinos )
  - Lamins and Rnf20 at the interface of cancer metabolism and epigenetics
    (Project Head Dobreva, Gergana )
Collaborative Research Centres
- Current projects
  - Angiocrine control of heart regeneration
    (Project Heads Marín-Juez, Rubén ; Stainier, Ph.D., Didier Y. ; Wu, Ph.D., Chi Chung )
  - BMP9/10-blood flow signaling crosstalk in safeguarding vessel integrity and organ functionality
    (Project Head Ola, Roxana )
  - FOXO transcription factors in PH: critical integrators of multiple immune signaling pathways driving pulmonary vascular and right ventricular remodeling
    (Project Heads Dobreva, Gergana ; Savai Pullamsetti, Soni )
  - Impact of endothelial-derived IncRNAs for cardiomyocyte signal transduction and the cardiac stress response
    (Project Head Heineke, Jörg )
  - Impact of the translation elongation factor 1a on cardiac growth and function
    (Project Head Heineke, Jörg )
  - Integrated Research Training Group ‘School of Angioscience’
    (Project Head Heineke, Jörg )
  - Interplay between epigenetics and metabolism in cardiac laminopathies
    (Project Head Dobreva, Gergana )
  - Mechanism-guided targeting of angiocrine signals to limit metastatic progression
    (Project Head Singhal, Mahak )
  - Transcriptional and epigenetic control of endothelial cell fate, plasticity and instructive signaling in the heart
    (Project Head Dobreva, Gergana )
  - Vascular control of organ-specific inflammation in cardiometabolic diseases
    (Project Head Stellos, Konstantinos )
- Completed projects
  - Role of endothelial ADAR1 in vascular growth and homeostasis
    (Project Head Stellos, Konstantinos )
  - Transcriptional complexes and chromatin reorganization in lineage choices and differentiation of embryonic stem cells
    (Project Head Dobreva, Gergana )
WBP Fellowship
- Completed projects
  - Shifting the balance: Mechanistic control of cell death dependent and independent functions of caspase-3 in epidermal stem cells.
    (Applicant Tisch, Nathalie )
Research Training Groups
- Completed projects
  - GRK 2099: Hallmarks of Skin Cancer: Tumor Microenvironment and Melanoma Immunity
    (Spokesperson Goerdt, Sergij )
International Research Training Groups
- Completed projects
  - GRK 1874: Diabetic Microvascular Complications (DIAMICOM)
    (Spokesperson Hammes, Hans-Peter )
Clusters of Excellence
- Completed projects
  - EXC 147: Cardio-Pulmonary System
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner ; Zeiher, Andreas Michael )
Clusters of Excellence (ExStra)
- Current projects
  - EXC 2026: Cardio-Pulmonary Institute (CPI)
    (Spokespersons Dimmeler, Stefanie ; Seeger, Werner )

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