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Institution
Universitätsklinikum Gießen und Marburg
Medizinische Klinik und Poliklinik II
Pneumologie, Gastroenterologie, Nephrologie und Internistische Intensivmedizin
Address
Klinikstraße 33
35392 Gießen
Deutschland
GERiT
This institution in GERiT
35392 Gießen
Projects
Research Grants
Current projects
Characterization of AT2 and LIF Heterogeneity and Role of Fgf10/Fgfr2b Signaling in the Maintenance of Adult Lung Homeostasis - Importance of Reciprocal Lipofibroblast/AT2 Stem Cell Interactions
(Applicant
Bellusci, Saverio
)
Justus-Liebig University Giessen Clinician Scientist Program in Biomedical Research
(Applicant
Günther, Andreas
)
Raising diagnostic accuracy and therapeutic perspectives in interstitial lung diseases
(Applicants
Eils, Roland
;
Günther, Andreas
)
Completed projects
Alveolar epithelial endoplasmic reticulum (ER)-stress in Idiopathic Pulmonary Fibrosis - identification of molecular trigger events and role in fibrotic repair
(Applicant
Günther, Andreas
)
Controlled Release von Wirkstoffen aus nanostrukturierten Carriersystemen in der Lunge
(Applicant
Gessler, Tobias
)
Einfluß einer inhalativen Surfactant-, Surfactant/Urokinase- oder Surfactant/Heparin-Applikation auf die Entwicklung einer Bleomycin-induzierten Lungenfibrose
(Applicant
Günther, Andreas
)
FGF10/FGFR2b signaling in lung emphysema as a target for lung regeneration
(Applicants
Bellusci, Saverio
;
Weißmann, Norbert
)
FGF10 signaling in distal/alveolar epithelial progenitor cells - role in lung fibrosis
(Applicant
Bellusci, Saverio
)
Fibroblast Growth factor signaling in lipofibroblast formation and transdifferentiation during normal lung development and fibrosis
(Applicant
Bellusci, Saverio
)
MicroRNA and Epithelial-Mesenchymal Interactions in Lung Development and Fibrosis
(Applicant
Bellusci, Saverio
)
Molecular Bases of Activated Myofibroblast (MYF) to Lipofibroblast (LIF) Phenotype switching during Fibrosis Resolution.
(Applicant
Bellusci, Saverio
)
Regulation of epithelial, pro-apoptotic Endoplasmic Reticulum (ER) stress in Idiopathic Pulmonary Fibrosis (IPF).
(Applicant
Korfei, Martina
)
Relative role and interdependence of urokinase and hepatocyte growth factor in mediating epithelial cell-protective effects in lung fibrosis
(Applicant
Ruppert, Ph.D., Clemens
)
Role of mononuclear phagocyte-epithelium crosstalk in alveolar repair
(Applicant
Lohmeyer, Jürgen
)
Heisenberg Fellowships
Completed projects
Pathomechanismen der respiratorischen Insuffizienz
(Applicant
Günther, Andreas
)
Clinical Research Units
Completed projects
Harnessing FGF-10 signaling to protect ER-stress alveolar epithelial cells against viral infection - impact on regenereration versus fibrosis
(Applicants
Bellusci, Saverio
;
El Agha, Ph.D., Elie
;
Günther, Andreas
)
HEALFIB: Eine randomisierte, doppel-blinde, Placebo-kontrollierte Multicenter-Studie zur Sicherheit und Effizienz von inhalativem Heparin bei Idiopathischer Pulmonaler Fibrose
(Applicant
Günther, Andreas
)
Impact of Btk/WASH/megalin on influenza virus infection and alveolar protein clearance in lung injury
(Applicants
Samakovlis, Christos
;
Vadasz, Istvan
)
KFO 118: Pathomechanisms and Therapy of Lung Fibrosis
(Spokesperson
Seeger, Werner
)
KFO 309: Virus-induced Lung Injury: Pathobiology and Novel Therapeutic Strategies
(Spokesperson
Seeger, Werner
)
Koordination der Klinischen Forschungsgruppe 118
(Applicant
Günther, Andreas
)
Pathogenetische Rolle und therapeutischer Nutzen des pulmonalen Surfactant-Systems bei fibrosierenden Lungenerkrankungen
(Applicant
Günther, Andreas
)
Untersuchungen zur klinischen Bedeutung und zum möglichen therapeutischen Nutzen antimikrobieller Proteine bei fibrosierenden Lungenerkrankungen
(Applicant
Markart, Philipp
)
Collaborative Research Centres
Current projects
Origin and fate of vascular myofibroblasts and smooth muscle cells during pulmonary vascular remodeling and reverse remodeling
(Project Heads
Bellusci, Saverio
;
El Agha, Ph.D., Elie
;
Hadzic, Stefan
)
Pathways for BMP9/10 responsiveness in smooth muscle cells, critical for pulmonary hypertension and right heart failure
(Project Heads
Bellusci, Saverio
;
Braun, Thomas
)
Right ventricular (RV) function in pulmonary hypertension and impact of targeted interventions on RV-PA (pulmonary artery) coupling
(Project Heads
Ghofrani, Hossein Ardeschir
;
Seeger, Werner
;
Tello, Khodr
)
Completed projects
Intravasale und extravasale/alveoläre Gerinnungsaktivierung in der Lunge: pathogenetische Bedeutung und differentielle Beeinflussung
(Project Heads
Günther, Andreas
;
Markart, Philipp
)
Pulmonale Transmigration von Monozyten und Expansion alveolärer Phagozytenpopulationen
(Project Head
Lohmeyer, Jürgen
)
SFB 547: Cardiopulmonary Vasculature
(Spokesperson
Seeger, Werner
)
Zentrale Aufgaben des Sonderforschungsbereichs
(Project Head
Seeger, Werner
)
Research Units
Completed projects
Controlled Release von Wirkstoffen aus nanostrukturierten Carriersystemen in der Lunge
(Applicant
Gessler, Tobias
)
CRC/Transregios
Completed projects
Development and function of respiratory macrophages and dendritic cell subsets during bacterial pneumonia
(Project Heads
Bauer, Stefan
;
Hackstein, Holger
;
Lohmeyer, Jürgen
)
Krüppel-like factors as regulators of inflammation in pneumococcal pneumonia
(Project Heads
Hippenstiel, Stefan
;
Lohmeyer, Jürgen
)
Research Training Groups
Completed projects
GRK 534: Biological Basis of Vascular Medicine
(Spokesperson
Piper, Hans Michael
)
International Research Training Groups
Completed projects
GRK 1062: Signalling Mechanisms in Lung Physiology and Disease (SMLPD)
(Spokesperson
Seeger, Werner
)
Clusters of Excellence
Completed projects
EXC 147: Cardio-Pulmonary System
(Spokespersons
Dimmeler, Stefanie
;
Seeger, Werner
;
Zeiher, Andreas Michael
)
Clusters of Excellence (ExStra)
Current projects
EXC 2026: Cardio-Pulmonary Institute (CPI)
(Spokespersons
Dimmeler, Stefanie
;
Seeger, Werner
)
Additional Information
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