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Institution
Charité - Universitätsmedizin Berlin
Campus Charité Mitte
Medizinische Klinik mit Schwerpunkt Hepatologie und Gastroenterologie (CCM)
Address
Charitéplatz 1
10117 Berlin
Deutschland
GERiT
This institution in GERiT
10117 Berlin
Projects
Research Grants
Current projects
Understanding and modulating hepatic macrophage functionality in non-alcoholic fatty liver disease
(Applicant
Tacke, Ph.D., Frank
)
Completed projects
CD39-dependent regulation of innate immune responses and modulation of exacerbated sterile inflammation in acute-on-chronic liver failure
(Applicant
Schmelzle, Moritz
)
Characterization of the Gastric Stem Cell Microenvironment and its Changes upon Infection with Helicobacter pylori
(Applicant
Sigal, Michael
)
Functional role of macrophage subsets in acetaminophen-induced acute liver failure and therapeutic implica-tions of its modulation by chemokine pathways
(Applicant
Tacke, Ph.D., Frank
)
Lipoprotein-Stoffwechsel. Einfluss der sekretorischen Phospholipase A2
(Applicant
Tietge, Uwe
)
Modulating hepatic iNKT cell accumulation and maturation via chemokine receptor CXCR6 for liver cancer prevention and treatment
(Applicant
Tacke, Ph.D., Frank
)
Platelets as initiators and mediators of liver fibrosis
(Applicant
Sahin, Hacer
)
Research Fellowships
Completed projects
Identifikation von Interaktionspartnern der nukleären Proteine Lamin A/C und Auswirkungen von Mutationen im LMNA-Gen auf diese Interaktionen
(Applicant
Lüdtke, Angelika
)
Interaction of Helicobacter pylori with Gastric Progenitor Cells
(Applicant
Sigal, Michael
)
Untersuchung der Differenzierung von Monozyten in dendritische Zellen in vivo
(Applicant
Tacke, Ph.D., Frank
)
Independent Junior Research Groups
Current projects
Interactions between epithelial Stem Cells and Bacteria in gastrointestinal Homeostasis and Carcinogenesis
(Applicant
Sigal, Michael
)
Completed projects
Migration, Differenzierung und funktionelle Rolle von Monozyten-Subpopulationen in vivo
(Applicant
Tacke, Ph.D., Frank
)
CRC/Transregios
Current projects
Impact of liver-specific TH activity on modulation of NAFLD and NASH
(Project Heads
Mai, Knut
;
Püngel, Tobias
;
Spranger, Joachim
;
Tacke, Ph.D., Frank
;
Wirth, Eva K.
)
Completed projects
FACS-based cell isolation and clinical translation
(Project Heads
Tacke, Ph.D., Frank
;
Weiskirchen, Ralf
)
Monocyte and macrophage subsets in liver fibrogenesis
(Project Head
Tacke, Ph.D., Frank
)
Priority Programmes
Completed projects
Spatial Organization of the Microbiota - Impact of Direct Bacterial Interaction with the Colonic Crypt Epithelium and Long-lived Stem Cells
(Applicants
Meyer, Thomas F.
;
Sigal, Michael
)
Major Research Instrumentation
Completed projects
FACS-Sorter mit UV-Laser
Spectral Multiphoton Microscope
Collaborative Research Centres
Current projects
Impact of gut-liver communication on hepatic macrophage composition and function
(Project Heads
Guillot, Adrien
;
Tacke, Ph.D., Frank
)
Clinical Trials
Current projects
End-ischemic hypothermic oxygenated (HOPE) or normothermic machine perfusion (NMP) compared to conventional cold storage (CCS) in donation after brain death (DBD) liver transplantation; a prospective multicenter randomized controlled trial (HOPE-NMP)
(Applicant
Lurje, Georg
)
Completed projects
Covered transjugular intrahepatic portosystemic stent shunt versus optimezed medical treatment for the secondary prevention of variceal bleeding in cirrhosis
(Applicant
Sauerbruch, Tilman
)
Research Training Groups
Completed projects
GRK 1208: Hormonal Regulation of Energy Metabolism, Body Weight and Growth
(Spokespersons
Grüters-Kieslich, Annette
;
Köhrle, Josef
)
Additional Information
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