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Philipps-Universität Marburg
Biomedizinisches Forschungszentrum
Institut für Immunologie

Address Hans-Meerwein-Straße 2
35043 Marburg
Deutschland

GERiT This institution in GERiT

35043 Marburg

Projects

Research Grants
- Completed projects
Research Fellowships
- Completed projects
  - Analyse der Spezifität verschiedener Toll-like Rezeptoren (TLR) für unterschiedliche Klassen von Pathogenen und die Effekte der Aktivierung von TLR auf die erworbene Immunität
    (Applicant Schnare, Markus )
Priority Programmes
- Completed projects
  - Inhibition of type Interferon production by murine leukemia retrovirus (MuLV)
    (Applicant Bauer, Stefan )
  - Molecular mechanisms of Toll-like receptor 9 activation and the role of TLRs in autoimmunity
    (Applicant Bauer, Stefan )
WBP Position
- Current projects
  - A to I RNA editing by ADAR1 is influenced by inositol hexaphosphate and prevents RIG-I activation
    (Applicant Venegas Solis, Francisco )
Collaborative Research Centres
- Completed projects
  - Analyse der Rolle des Migrations-Inhibitions-Faktors (MIF) bei Stress-Reaktionen im ZNS und der Peripherie
    (Project Head Gemsa, Diethard )
  - RNA als mikrobielles Erkennungsmuster
    (Project Head Bauer, Stefan )
  - Role of receptor specificity and membrane fusion activity of influenza viruses in host range, cell tropism and pathogenicity
    (Project Heads Bauer, Stefan ; Matrosovich, Ph.D., Mikhail )
  - Role of the RNA modifications 2'-O-methylation and N6-methyladenosine in viral pathogenicity
    (Project Head Bauer, Stefan )
CRC/Transregios
- Current projects
  - Role of self RNA in immune sensing and tolerance
    (Project Heads Bauer, Stefan ; Zillinger, Thomas )
- Completed projects
  - Antiviral IFNs and NK cells in COVID-19
    (Project Heads Bauer, Stefan ; Diefenbach, Andreas ; Opitz, Bastian )
  - Development and function of respiratory macrophages and dendritic cell subsets during bacterial pneumonia
    (Project Heads Bauer, Stefan ; Hackstein, Holger ; Lohmeyer, Jürgen )
  - Dissecting the role of RNA in host defence and immune-subversion by SARS-CoV-2
    (Project Heads Bauer, Stefan ; Sander, Leif Erik ; Schulte, Leon )
  - The role of TLR9 and TIR8 in the development of allergic lung disease
    (Project Head Bauer, Stefan )
Clinical Research Units
- Current projects
  - KFO 325: Clinical relevance of tumor-microenvironment interactions in pancreatic cancer
    (Spokesperson Gress, Thomas Mathias )
  - Role of pattern recognition receptors and microbiome-derived growth promoting signals in tumor-immune cell interaction in PDAC
    (Applicants Bauer, Stefan ; Buchholz, Malte )
- Completed projects
  - KFO 309: Virus-induced Lung Injury: Pathobiology and Novel Therapeutic Strategies
    (Spokesperson Seeger, Werner )
  - Profiling anti-influenza activities of the pathogen recognition receptor RIG-I: Novel targets for antiviral intervention strategies
    (Applicants Bauer, Stefan ; Weber, Friedemann )

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