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Institution
Justus-Liebig-Universität Gießen
Fachbereich - Biologie und Chemie
Institut für Biochemie
Address
Heinrich-Buff-Ring 17
35392 Gießen
Deutschland
GERiT
This institution in GERiT
35392 Gießen
Projects
Research Grants
Current projects
Functional analysis of interactions of the SARS-CoV-2 genome with microRNAs and virus inhibition by circular RNAs as a novel therapeutic concept
(Applicant
Roßbach, Oliver
)
Function of the splicing factor Msl5 in transcription and nuclear mRNP biogenesis
(Applicant
Sträßer, Katja
)
Completed projects
Biochemie unspezifischer Nukleasen und ihrer Inhibitoren
(Applicant
Pingoud, Alfred
)
Charakterisierung der Recyclingphase des humanan Spleißosom-Zyklus
(Applicant
Bindereif, Albrecht
)
Coupling of transcription to mRNA export
(Applicant
Sträßer, Katja
)
Einzelmolekülstudien zur linearen Diffusion von sequenzspezifischen Endonukleasen
(Applicant
Wende, Wolfgang
)
Enzymologie der intein-codierten homing-Endonuklease PI-SceI aus Saccharomyces cerevisiae
(Applicant
Pingoud, Vera
)
Function of an mRNA-binding protein in RNA polymerase III transcription
(Applicant
Sträßer, Katja
)
Mechanismus der DNA-Erkennung und -Spaltung durch Restriktionsenzyme
(Applicant
Pingoud, Alfred
)
Novel RNA-mediated regulatory roles of the human hnRNP L proteins
(Applicant
Bindereif, Albrecht
)
Protein-Protein-Interaktionen im DNA-mismatch-Reparatursystem: site-directed crosslink und Fluoreszenz-Resonanzenergie-Transfer Studien
(Applicant
Friedhoff, Peter
)
RBM28: comprehensive analysis of its role in human disease and neuroepithelial tissue development
(Applicant
Bindereif, Albrecht
)
Regulation und Enzymologie apoptotischer Nukleasen
(Applicant
Pingoud, Alfred
)
Regulatory mechanisms in the recycling phase of the spliceosome cycle: combining the human and zebrafish systems
(Applicant
Bindereif, Albrecht
)
Reverse footprint - Analyse der Kontakte in DNA-Protein-Komplexen
(Applicant
Pingoud, Alfred
)
Spliceosomal small nuclear ribonucleoproteins in trypanosomes: SMN-directed assembly of Sm core complexes and functional role of core variations
(Applicant
Bindereif, Albrecht
)
Spliceosomal small nuclear ribonucleoproteins in trypansomes: Genomwide analysis of role of U1 snRPN proteins in mRNA processing
(Applicant
Bindereif, Albrecht
)
Struktur, Funktion und Evolution von Typ II Restriktionsenzymen
(Applicant
Pingoud, Alfred
)
Struktur und Dynamik des DNA-mismatch-Reparatursystems aus Escherichia coli
(Applicant
Friedhoff, Peter
)
Priority Programmes
Completed projects
Enzymologie des GTP-abhängigen Restriktionssystems McrBC aus E. coli K-12
(Applicant
Pingoud, Alfred
)
Generation of homing endonucleases of pre-defined specificity by directed evolution
(Applicant
Wende, Wolfgang
)
Identification and functional analysis of RNA-binding sites in proteins involved in nuclear mRNP assembly in S. cerevisiae
(Applicants
Sträßer, Katja
;
Urlaub, Henning
)
Investigating early messenger ribonucleoprotein complex remodelling with RNA interactome capture
(Applicant
Kilchert, Cornelia
)
The multidomain RNA-binding protein IMP3: combinatorial RNA recognition and functions during mRNP biogenesis
(Applicant
Bindereif, Albrecht
)
Research Units
Current projects
Vesicle-mediated RNA transfer: from factors and mechanisms to functions
(Applicant
Schäfer, Patrick
)
Completed projects
Regulation of mammalian mRNA splicing by CA repeat enhancer elements
(Applicant
Bindereif, Albrecht
)
Independent Junior Research Groups
Completed projects
Mechanisms of substrate selectivity of the nuclear RNA exosome complex.
(Applicant
Kilchert, Cornelia
)
Collaborative Research Centres
Completed projects
Cis und trans mRNA-Spleißen in Trypanosomen
(Project Head
Bindereif, Albrecht
)
Degradation of irreversibly stalled RNA polymerase II
(Project Head
Sträßer, Katja
)
Research Fellowships
Completed projects
Mechanisms of Telomerase RNA Processing and Formation of Ribonucleoprotein Particles in Saccharomyces cerevisiae
(Applicant
Kilchert, Cornelia
)
Research Training Groups
Current projects
GRK 2355: Regulatory networks in the mRNA life cycle: from coding to noncoding RNAs
(Spokesperson
Sträßer, Katja
)
Completed projects
GRK 370: Biochemistry of Nucloeprotein Complexes
(Spokesperson
Pingoud, Alfred
)
International Research Training Groups
Completed projects
GRK 1384: Enzymes and Multienzyme Complexes Acting on Nucleic Acids
(Spokesperson
Friedhoff, Peter
)
Additional Information
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