Project Details
Projekt
GRK 1216: Intra- and Intercellular Transport and Communication
Subject Area
Basic Research in Biology and Medicine
Term
from 2006 to 2015
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 948344
Understanding cell-cell communication, cell polarity and cellular compartmentalisation is one of the central themes in modern cell biology. The molecular details of underlying transport mechanisms, which lead to macromolecule sorting and, therefore, to specific localisations of proteins and lipids, can now be worked out by combinations of new techniques and improved techniques, which involve cell biology, biochemistry as well as genomics.
In Marburg, five groups from the Biology and two from the Medicine Department of the Philipps-University, three groups from Marburg´s Max Planck Institute for Terrestrial Microbiology and four junior groups have teamed up to establish this Research Training Group. These groups work as an interdisciplinary consortium to address "Intra- and inter-cellular transport and communication".
In particular, the college's research focusses on mechanisms underlying cell-cell interactions, establishment of cell polarity and intracellular targeting of proteins and lipids. The projects are undertaken on model organisms, for which genomic data are available and tools in cell biology can be applied. The interdisciplinary approach is intended to lead to an exchange of techniques as well as model organisms between the involved research teams. This will assure that the best model can be chosen for a given problem. And PhD students can be reassigned if their original model does not lead to a means of deriving answers. To allow PhD students to choose the right technique or system, they must participate in advanced training courses. These will be specifically tailored to allow them to use databases in connection with functional arrays, learn about specific advantages of all model systems represented in the Research Training Group, and expose them to up to date techniques in microscopy and protein analysis.
In their study programme students participate in seminars, lectures and workshops, visit international conferences, join an international leading laboratory for a period of three months, and organise, together with the group leaders, an international meeting. The scientific themes as well as the training of the fellows are integrated into the scientific infrastructure of Marburg and will lead to a fruitful and mutual exchange between the Research Training Group and other initiatives.
In Marburg, five groups from the Biology and two from the Medicine Department of the Philipps-University, three groups from Marburg´s Max Planck Institute for Terrestrial Microbiology and four junior groups have teamed up to establish this Research Training Group. These groups work as an interdisciplinary consortium to address "Intra- and inter-cellular transport and communication".
In particular, the college's research focusses on mechanisms underlying cell-cell interactions, establishment of cell polarity and intracellular targeting of proteins and lipids. The projects are undertaken on model organisms, for which genomic data are available and tools in cell biology can be applied. The interdisciplinary approach is intended to lead to an exchange of techniques as well as model organisms between the involved research teams. This will assure that the best model can be chosen for a given problem. And PhD students can be reassigned if their original model does not lead to a means of deriving answers. To allow PhD students to choose the right technique or system, they must participate in advanced training courses. These will be specifically tailored to allow them to use databases in connection with functional arrays, learn about specific advantages of all model systems represented in the Research Training Group, and expose them to up to date techniques in microscopy and protein analysis.
In their study programme students participate in seminars, lectures and workshops, visit international conferences, join an international leading laboratory for a period of three months, and organise, together with the group leaders, an international meeting. The scientific themes as well as the training of the fellows are integrated into the scientific infrastructure of Marburg and will lead to a fruitful and mutual exchange between the Research Training Group and other initiatives.
DFG Programme
Research Training Groups
Applicant Institution
Philipps-Universität Marburg
Spokesperson
Professor Dr. Uwe Gallus Maier
Participating Researchers
Professor Dr. Michael Bölker; Professor Dr. Stephan Herzig; Professor Dr. Ralf Jacob; Professorin Dr. Regine Kahmann; Professor Dr. Roland Lill; Professor Dr. Klaus Lingelbach (†); Professorin Dr. Andrea Susanne Maisner; Professor Dr. Hans-Ulrich Mösch; Professorin Dr. Susanne Oenel; Professorin Dr. Renate Renkawitz-Pohl; Professorin Dr. Lotte Sogaard-Andersen; Professor Dr. Martin Rudolf Thanbichler; Dr. Stefan Zauner
