Die Regulation des oxidativen Energiemetabolismus in Astrozyten im Wechselspiel mit neuronaler Aktivität

• Antragstellerin: Dr. Susanne Arnold
• Fachliche Zuordnung: Molekulare Biologie und Physiologie von Nerven- und Gliazellen
• Förderung: Förderung von 2001 bis 2007
• Projektkennung: Deutsche Forschungsgemeinschaft (DFG) - Projektnummer 5299828

• Erstellungsjahr: 2009

Zusammenfassung der Projektergebnisse

Keine Zusammenfassung vorhanden

Projektbezogene Publikationen (Auswahl)

• (2001). Cytochrome c oxidase and the regulation of oxidative phosphorylation. 3,446 Chembiochem Eur. J. Chem. Biol. 2, 392-403
  Ludwig B., Bender E., Arnold S., Hüttemann M., Lee I., Kadenbach B.
  
• (2001). Minireview-Hypothesis. New control of mitochondrial membrane potential and ROS formation. 2,840 Biol. Chem. 382, 1629-1636
  Lee I., Bender E., Arnold S., Kadenbach B.
  
• (2003). Stress modifiziert den Energiemetabolismus und verursacht Krankheiten. BioSpektrum 6, 704-707
  Arnold S., Kadenbach B.
  
• (2004). The possible role of cytochrome c oxidase in stress-induced apoptosis and degenerative diseases. 3,835 Biochim. Biophys. Acta 1655, 400-408
  Kadenbach B., Arnold S., Lee I., Hüttemann M.
  
• (2005). BI-1 protects cells from oxygen glucose deprivation by reducing the calcium content of the endoplasmic reticulum. 8,254 Cell Death Differ. 12, 304-306
  Westphalen B.C., Wessig J., Leypoldt F., Arnold S., Methner A.
  
• (2005). Estrogen suppresses the impact of glucose deprivation on astrocytic calcium levels and signaling independently of the nuclear estrogen receptor. 4,377 Neurobiol. Dis. 20. 82-92
  Arnold S.
  
• (2006). Effect of hypoxia on the transcription pattern of subunit isoforms and the kinetics of cytochrome c oxidase in cortical astrocytes and cerebellar neurons. 4,451 J. Neurochem. 99. 937-951
  Horvat S., Beyer C., Arnold S.
  
• (2006). Estrogen and the development and protection of nigrostriatal dopaminergic neurons: Concerted action of a multitude of signals, protective molecules, and growth factors. 6,481 Front. Neuroendocrinol. 27, 376-390
  Kipp M., Karakaya S., Pawlak J., Araujo-Wright G., Arnold S., Beyer C.
  
• (2008). Expression of enzymes involved in the prostanoid metabolism by cortical astrocytes after LPS-induced inflammation. 1,735 J. Mol. Neurosci. 34, 177-185
  Johann S., Kampmann E., Denecke B., Arnold, S., Kipp M., Mey J., Beyer C.
  
• (2008). Gender-specific regulation of mitochondrial fusion and fission gene transcription and viability of cortical astrocytes by steroid hormones. 2,801 J. Mol. Endocrmol.
  Arnold S., Araújo G.W., Beyer C.
  
• (2008). Oestrogen influences on mitochondrial gene expression and respiratory chain activity in cortical and mesencephalic astrocytes. 2,588 J. Neuroendocrinol. 20. 930-941
  Araújo G.W., Beyer C., Arnold S.