Intervening in circuits for cognitive resource allocation in primates (C05)

• Subject Area: Cognitive, Systems and Behavioural Neurobiology ; Human Cognitive and Systems Neuroscience
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 425899996

Local but interconnected circuits in visual, parietal and prefrontal cortex provide the neural resources for primates to compute perceptual decisions. Combining theoretical and empirical approaches, we probe - neuron to behaviour - resource allocation by functional connectivity (FC) changes in macaques. We alter frontoparietal FC with focused ultrasound. Neural mechanisms are inferred by network models of monkeys’ own connectivity data and validated against empirical counterparts. We predict FC interventions to adjust the correlation structure of neural population encoding and thus alter resource allocation and cognitive performance.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1436: Neural resources of cognition
• Applicant Institution: Otto-von-Guericke-Universität Magdeburg
• Project Heads: Professorin Dr. Kristine Krug; Professorin Dr. Petra Ritter