Role of the aryl hydrocarbon receptor in hepatic immune regulation (P03*)

• Subject Area: Nutritional Sciences
• Term: from 2018 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 80750187

The aryl hydrocarbon receptor (AhR) is an important immune modulator that can integrate signals from environmental, microbial or metabolic ligands into the immune response. We will explore the role of AhR in the regulation of hepatic immune tolerance and inflammation, both at the level of T cells and hepatic antigen presenting cells. Furthermore, we will evaluate the therapeutic potential of AhR ligands for the treatment of inflammatory liver diseases.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 841: Liver Inflammation: Infection, Immune Regulation and Consequences
• Applicant Institution: Universität Hamburg
• Project Head: Dr. Antonella Carambia