Mortality and associated characteristics of an adult population with mental disorders

• Applicants: Professor Dr. Ulrich John; Professor Dr. Christian Meyer; Professor Dr. Hans-Jürgen Rumpf
• Subject Area: Epidemiology and Medical Biometry/Statistics
• Term: from 2017 to 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 329858602

Evidence shows that mentally ill persons among the general population die earlier than those without mental disease. Limitations of research include that epidemiological studies did not use modern standardized psychiatric diagnostic systems, and that detailed information about health risk behaviors are missing, particularly about tobacco smoking and alcohol consumption. Findings according to somatoform disorders are missing, and we lack knowledge about utilization of psychiatric care and other medical care with respect to mortality risks. Therefore, work that we did before includes one baseline survey of a random sample of 4,075 adults at age 18 to 64 in the general population of a German region in the year 1996. We published a second study about the mortality risks of those who had been diagnosed at baseline as ever having fulfilled the criteria of alcohol dependence in lifetime before compared to those without such a diagnosis. We concluded from this second study that the planned project will be feasible. Its aims include, first, to analyze mortality rates per specific diagnosis among three subgroups of the sample - individuals with substance use disorders, individuals with affective disorders, and individuals with somatoform disorders - 20 years after baseline. The second aim is to compare those those who are still alive with those have been deceased including time to death according to single characteristics of tobacco smoking and alcohol risk drinking. Third, we will analyze whether the same lifetime exposure to tobacco smoke with or without nicotine dependence is related to different mortality risks. Fourth, mortality risks among those with somatoform disorders are to be analyzed compared to those without. Fifth, utilization of psychiatric and further medical care will be analyzed among patients with single disorders. The work program includes the collection of vital status data, i. e. whether a single person has been deceased, and if, at which date. Causes of death are to be analyzed from death certificates. Work will particularly include address searches and publication of the data according to each single study aim.

• DFG Programme: Research Grants