Are Stereoelectronic Effects Additive or Cooperative? (A09)

• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 2014 to 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 104405829

Stereoelectronic effects are abundant in nature and are also key elements in organic chemistry. The goal of the project is to explore whether stereoelectronic effects are additive or cooperative. To this end, various multi-vicinal fluorinated alkanes which are constructed from CHF-entities with defined configuration will be studied. These little explored functionalities will eventually be incorporated into catalytically and biologically interesting compounds. Realization of this project demands for a multidisciplinary approach within the frame of the SFB: syntheses and structural analysis will challenge the analytical institutions of the WWU Münster and also computational chemistry will be used to understand and quantify the addressed interactions. Finally, the novel compounds will be applied to enantioselective catalysis.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 858: Synergetic Effects in Chemistry - From Additivity towards Cooperativity
• Applicant Institution: Universität Münster
• Project Head: Professor Dr. Ryan Gilmour