Stimulation of bone defect and fracture healing in systemically impaired bone by biomaterials and metallic implants ((19) T02)

• Subject Area: Biomaterials ; Orthopaedics, Traumatology, Reconstructive Surgery
• Term: from 2010 to 2019
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 107540325

In the third funding period, T2 intends to provide sufficient data for the use of biomaterials to stimulate fracture healing in osteoporotic fracture defects and for biomaterials for the local antiproliferative treatment against multiple myeloma cells for their clinical application in the future by an extension of the observation period from 6 to 16 weeks in a rat model. The second goal is the in vivo evaluation in animal models to analyse the respective material developments of TFP1 and TFP2 after previously conducted in vitro experiments according to the „pyramid principle“ in close cooperation with with two transfer projects.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 79: Materials for Tissue Regeneration within Systemically Altered Bone
• Applicant Institution: Justus-Liebig-Universität Gießen
• Project Heads: Professor Dr. Volker Alt; Professor Dr. Reinhard Schnettler, until 6/2014; Dr. Ulrich Thormann