Project Details
Projekt
Regulation of the T cell response during malaria (B04)
Subject Area
Immunology
Term
from 2010 to 2021
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 80750187
Protection against malaria can be achieved by experimental induction of liver-stage infection when the subsequent blood-stage is prevented by using attenuated sporozoites or by antimalarial treatment. The blood-stage is accompanied by induction of Tr1-like cells. These cells will be further characterized by “next-generation sequencing” and high-content flow cytometry. Different subsets of Tr1-like cells will be tested for their regulatory capacity especially wit regard to their capability to prevent liver-stage immunity.
DFG Programme
Collaborative Research Centres
Applicant Institution
Universität Hamburg
Project Heads
Privatdozent Thomas Jacobs, Ph.D.; Dr. Maria Sophia Mackroth
