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Professor Dr. Argyris Papantonis

Address Universitätsmedizin Göttingen
Institut für Pathologie
Robert-Koch-Straße 40
37075 Göttingen

Projects

As Applicant
- Current projects
  - Investigating the role of human topoisomerases in maintaining chromosome topology and preventing genomic instability (Research Grants)
  - Dissecting the principles guiding CTCF condensate formation in cellular ageing (Priority Programmes)
  - Exploring the contribution of RNA polymerases to mammalian 3D genome architecture (Priority Programmes)
  - Coordination Funds (Priority Programmes)
  - Inducing therapeutic vulnerabilities in patient-derived PDAC models by targeting the metabolome-to-3D chromatin axis (Clinical Research Units)
  - Dissecting functional master-enhancer regimes driving inflammatory stimulation (Research Grants)
- Completed projects
  - Exploring 3D miRNA networks during cellular aging. (Research Grants)
  - Nucleotide-resolution mapping of nascent RNA revisits the principles of transcriptional reorganization of the human genome upon signaling. (Research Grants)
  - Recursive splicing and mRNA polyadenylation regulatory circuits govern homeostasis and cell cycle potency of pluripotent cells. (Priority Programmes)
As Spokesperson
- Current projects
  - SPP 2202: Spatial Genome Architecture in Development and Disease (Priority Programmes)
As Participating Researcher
- Completed projects
  - GRK 2407: Inflammatory and cellular stress signaling: Switches to vascular dysfunction (Research Training Groups)
As Project Head
- Current projects
  - Multifunctional chromatin factors in control of gene expression and nuclear architecture (Collaborative Research Centres)
  - KFO 5002: Deciphering genome dynamics for subtype-specific therapy in pancreatic cancer (Clinical Research Units)
  - Maintaining gene expression fidelity in response to DNA- and RNA-protein crosslinks (Collaborative Research Centres)
- Completed projects
  - High mobility group B factors as regulators of genomic architecture via CTCF clustering Argyris Papantonis (CRC/Transregios)
As Co-Investigator
- Current projects
  - Molecular mechanisms and cellular functions of the CpG island-binding protein SAMD1 (Research Grants)
  - Minimal supervision for phase-contrast microscopy segmentation (Research Grants)

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