Project Details

Professor Dr. Stephan J. Sigrist

Address Freie Universität Berlin
Fachbereich Biologie, Chemie, Pharmazie
Institut für Biologie
Königin-Luise-Straße 1-3
14195 Berlin

Projects

As Applicant
- Current projects
  - Non-cell autonomous regulation of synaptic upscaling by neuronal autophagy (Research Units)
  - From imprecise synapse seeding to robust synapse formation by stabilization mechanisms of early molecular scaffolds (Research Units)
  - Presynaptic plasticity in the control of mushroom body memory formation (Research Units)
  - Autophagy-Enhancers to reduce sleep disturbances: a combined approach (Research Grants)
  - Enabling Identification and Impact of Synaptic Weight in Functional Networks (Research Grants)
- Completed projects
  - A Drosophila Grip-Homologue in synaptic development and plasticity: an integrative study (Research Grants)
  - Glutamate receptor field dynamics (Research Grants)
  - Struktur-Funktions Analyse der aktiven Zone in Drosophila (Research Grants)
  - Monoamine secretion and synaptic modulation during olfactory conditioning in Drosophila (Research Units)
  - Active zone core proteins in interaction with synaptic Ca2+ channels (Research Grants)
  - Nanoscale cellular and molecular fingerprints of synaptic diversity (Research Grants)
  - The role of hypusination-dependent translation for brain aging (Research Grants)
As Leader
- Completed projects
  - STED Konfokalmikroskop (Major Research Instrumentation)
  - 2-Photonen-Mikroskop (Major Research Instrumentation)
As Spokesperson
- Completed projects
  - SFB 958: Scaffolding of Membranes: Molecular Mechanisms and Cellular Functions (Collaborative Research Centres)
As Participating Researcher
- Current projects
  - EXC 2049: NeuroCure (Clusters of Excellence (ExStra))
- Completed projects
  - GRK 1123: Cellular Mechanisms of Learning and Memory Consolidation in the Hippocampal Formation (Research Training Groups)
As Project Head
- Current projects
  - Lipid-mediated mitochondrial dysfunction in HFpEF during obesity (Collaborative Research Centres)
  - Homeostatic presynaptic plasticity in memory consolidation and sleep of the aging brain (Collaborative Research Centres)
  - High resolution analysis of active zone cytomatrix remodeling (CRC/Transregios)
- Completed projects
  - Bedeutung des Drosophila GRIP-Homologen für Entwicklung und Plastizität der neuromuskulären Synapse (Collaborative Research Centres)
  - Synaptische Veränderungen und olfaktorisches Lernen von Drosophila melanogaster (Collaborative Research Centres)
  - Mechanismen der Akkumulation von Ca2+-Kanälen an aktiven Zonen (Collaborative Research Centres)
  - Glutamate receptor trafficking in the integration of short- and long-term synaptic plasticity (Collaborative Research Centres)
  - Active Zone Protein Transport and Autism (Collaborative Research Centres)
  - "Closing the cycle": Sub-modules in synaptic vesicle membrane targeting, fusion and endocytosis (Collaborative Research Centres)
  - In vivo analysis of active zone assembly (Collaborative Research Centres)
  - Organization of the synaptic active zone scaffold by Bruchpilot and RIM-binding protein (Collaborative Research Centres)
  - Central Tasks-SFB Headquarters and Administration (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Identification and characterization of genes encoding proteins with polar expression in different Drosophila cells (Priority Programmes)
As Co-Investigator
- Completed projects
  - The molecular mechanisms of aminergic release at “en-passent” type II synaptic terminals of the fruit fly (Drosophila melanogaster). (Research Grants)

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Hauptnavigation

Professor Dr. Stephan J. Sigrist

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Stephan J. Sigrist

Additional Information

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