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Professor Dr. Donat Kögel

Address Goethe-Universität Frankfurt am Main
Neuroscience Center
Abteilung Experimentelle Neurochirurgie
Theodor-Stern-Kai 7
60596 Frankfurt am Main

Projects

As Applicant
- Current projects
  - Novel strategies for the targeted elimination of glioblastoma stem-like cells (Research Grants)
  - Fatty Acid Synthase and lipophagy as therapeutic targets of glioblastoma (Research Grants)
- Completed projects
  - Investigating the roles of endogenous APP family members in stress signaling and aging (Research Units)
  - Novel therapeutic strategies in gliomas, based on the inhibition of the oncogenic signal transduction pathways Pim-1 / STAT3 through RNA interference and miRNA replacement (Research Grants)
  - The role of secreted APP in modulation of the Akt survival signaling pathway and neuroprotection (Research Grants)
  - Targeting the therapy resistance factors BAG3 und Bcl-xL in solid tumors (Research Grants)
As Project Head
- Current projects
  - Interplay between autophagy and inflammatory cell death in organ fibrogenesis (Collaborative Research Centres)
- Completed projects
  - Organelle-specific autophagy pathways in regulation of cell death (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Experimentelle Therapie von Gliomen: Interferenz mit der Expression und der Funktion des Transkriptionsfaktors Stat3 (signal transducer and activator of transcription) in Kulturzellen und in immunokompetenten, syngenen Mäusen (Research Grants)

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