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Project Details

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Professorin Dr. Christine Klein

Address Universität zu Lübeck
Institut für Neurogenetik
Ratzeburger Allee 160
23562 Lübeck

Projects

As Applicant
- Current projects
  - Coordination Funds (Research Units)
  - Reduced penetrance in Parkin and PINK1 deficiency: Inflammation as a Parkinson’s disease penetrance modifier (Research Units)
  - Identifying Parkinson’s disease penetrance-modifying factors in the population-based Cooperative Health Research in South Tyrol (CHRIS) cohort (Research Units)
  - Investigating the impact of COVID-19 on Parkinson's disease (Research Grants)
  - Uncovering novel causes and modifiers of amyotrophic lateral sclerosis by nuclear and mitochondrial genome sequencing (Research Grants)
- Completed projects
  - Molekulargenetische und proteinbiochemische Untersuchungen zur Ätiologie des Parkinson-Syndroms mit frühem Beginn (Research Grants)
  - Neurologie (Heisenberg Fellowships)
  - Role of the PRKRA-(DYT16) gene in different forms of dystonia (Research Grants)
  - The role of endogenous PINK1 and Parkin mutations in human dopaminergic neurons (Research Grants)
  - Molecular characterization of TUBB4 mutations (Research Grants)
  - Elucidating novel genetic causes of dystonia by large-scale sequencing (Research Grants)
As Spokesperson
- Current projects
  - FOR 2488: Reduced penetrance in hereditary movement disorders: Elucidating mechanisms of endogenous disease protection (Research Units)
As Participating Researcher
- Current projects
  - EXC 2167: Precision Medicine in Chronic Inflammation (PMI) (Clusters of Excellence (ExStra))
- Completed projects
  - GSC 235: Graduate School for Computing in Medicine and Life Sciences (Graduate Schools)
As Project Head
- Completed projects
  - Generation of a reference cohort with extreme eating behaviour (CRC/Transregios)
  - Characterization of action control networks in genetically determined parkinsonism (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Identifizierung genetischer Ursachen des "Restless legs"-Syndroms (Research Grants)
  - Genetic risk factors of musician´s dystonia (Research Grants)
  - Epidemiologie nicht-motorischer Symptome beim Parkinsonsyndrom: Häufigkeit, Charakteristika, Spezifität und Verlauf (Research Grants)
As Co-Investigator
- Current projects
  - Clinician Scientist School Lübeck: Connecting Brain, Metabolism, and Inflammation (BMI) – Mechanisms and Disease Expression (Research Grants)

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