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Professor Matthias Wilmanns, Ph.D.

Address Europäisches Laboratorium für Molekularbiologie (EMBL)
Außenstelle Hamburg
Notkestraße 85
22603 Hamburg

Projects

As Applicant
- Current projects
  - Time-resolved catalysis and allostery in tryptophan synthase as model for bi-enzyme machineries with an active sites-connecting product/substrate tunnel (Research Grants)
- Completed projects
  - Aktivierung und katalytischer Mechanismus von Glutamin-Amidotransferasen, untersucht an der Imidazolglycerinphosphat-Synthase aus Thermotoga maritima (Research Grants)
  - Active site recruitment in an ancestral, bifunctional ProFAR/PRA isomerase (Priority Programmes)
  - Structural Basis of Z-disc Protein/Protein Networks and Functional Implications (Research Units)
  - Interrogation of structure-function relationships in network formation of von Willebrand Factor domains by X-ray crystallography (Research Units)
  - Structural and Functional Characterization of the RAI2 Protein (Research Grants)
  - Structural biology of the translocation pore of the peroxisomal protein import machinery (Research Units)
  - Unraveling the Mechano-Regulation of Von Willebrand Factor (Research Grants)
  - Combined high-resolution structural and functional characterization of the multi-layered bipartite NEPH-NEPHRIN based slit diaphragm (Research Grants)
As Project Head
- Current projects
  - Structural and functional characterization of podocyte antigens in autoantibody-mediated glomerulonephritis (Collaborative Research Centres)
As Participating Person
- Completed projects
  - Understanding mediated/direct electron transfer and solvent resistance by iterative cycles of directed monooxygenase evolution and refinement of computational models (Priority Programmes)

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