Project Details

Professor Dr. Georg Häcker

Address Universitätsklinikum Freiburg
Department für Medizinische Mikrobiologie, Virologie und Hygiene
Hermann-Herder-Straße 11
79104 Freiburg

Projects

As Applicant
- Current projects
  - Analysis and role of the inhibition of apoptosis by the Chlamydia trachomatis OmpA protein (Research Grants)
  - The mitochondrial intermembrane space protein Smac/DIABLO in signal transduction and immune response (Research Grants)
  - Activation of cGAS/STING by the Caspase-Activated DNAse (Research Grants)
  - Sub-lethal mitochondrial outer membrane permeabilization: mechanisms and regulation in bacterial infection (Research Grants)
- Completed projects
  - Apoptosis in the interaction of the intracellular bacterium Chlamydia Pneumoniae and the infected host cell (Research Grants)
  - The role of bacteria-induced cell death in phagocytes for the development of the anti-bacterial immune response (Priority Programmes)
  - The role of cell death induced in microbial infections for the development of the antimicrobial immune response (Research Grants)
  - Mechanism and importance of mitochondrial import of BH3-only proteins during apoptosis (Research Grants)
  - Molecular function and biological importance of the protease CPAF during infection of human cells by Chlamydia (Research Grants)
  - Activated T cell death: molecular mechanisms and implications of T cell function (Research Grants)
  - Apoptosis Induction and Inhibition by Modified Vaccinia Virus Ankara during Infection of Human and Mouse Cells (Research Grants)
  - Establishment and maintenance of the chlamydial inclusion: requirement for septins and the inhibition of host cell translation (Priority Programmes)
  - Evasion of apoptosis and immune recognition during host adaptation of Chlamydia and Chlamydia-like bacteria (Research Grants)
  - The role of pro-apoptotic BH3-only proteins in survival and differentiation of lymphocytes (Research Grants)
  - Innate lymphocytes in the female genital tract and their role in chlamydial infection (Priority Programmes)
  - Molecular activation and activity of the BH3-only protein Bim (Research Units)
  - Molecular analysis of apoptosis inhibition by Chlamydia trachomatis (Research Grants)
  - The mitochondrial apoptosis apparatus in the detection of microbial infection. (Research Grants)
  - Mitochondrial complexes containing the pro-apoptotic Bcl-2-family protein Bim: structure and regulatory function (Research Grants)
As Participating Researcher
- Current projects
  - GRK 2606: Understanding protease functions in cellular pathways through discovery and analysis of protease substrates (ProtPath) (Research Training Groups)
- Completed projects
  - GRK 333: Biology of Human Diseases (Research Training Groups)
As Project Head
- Current projects
  - Large BCL-2-family protein complexes on the outer mitochondrial membrane and their role in the decision to undergo apoptosis (CRC/Transregios)
- Completed projects
  - Untersuchungen zur Integration der Signaltransduktionswege von Zellaktivierung und Zelltod in haematopoetischen Zellen (Collaborative Research Centres)
  - Molecular pathways and immunological consequences of microbe- induced all death in the innate immune system (Collaborative Research Centres)
  - Immunodeficiencies due to neutrophil dysfunction: molecular analyses of signalling pathways (Collaborative Research Centres)

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Hauptnavigation

Professor Dr. Georg Häcker

Additional Information

Servicenavigation

Hauptnavigation

Professor Dr. Georg Häcker

Additional Information

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