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Institution
Leibniz-Institut für Arbeitsforschung an der TU Dortmund (IfADo)
Forschungsbereich Toxikologie
Address
Ardeystraße 67
44139 Dortmund
Deutschland
GERiT
This institution in GERiT
44139 Dortmund
Projects
Research Grants
Current projects
Embryonic lethality upon targeted disruption of a glycerophosphodiesterase: unravelling the role of Gpcpd1 in foetal mouse erythropoiesis
(Applicant
Marchan, Ph.D., Rosemarie
)
Functional imaging to explore a so far unconsidered mechanism of acetaminophen hepatotoxicity
(Applicant
Ghallab, Ahmed
)
Intracellularly-derived lysophosphatidic acid (LPA) and glycerophospholipid metabolism in ovarian cancer
(Applicant
Marchan, Ph.D., Rosemarie
)
Mechanisms causing cholemic nephropathy
(Applicant
Hengstler, Jan G.
)
Mechanisms of the formation of ductular reactions in cholestatic liver disease
(Applicants
Hengstler, Jan G.
;
Höhme, Stefan
)
Completed projects
Characterising a role for EDI3 in metastasis in vivo
(Applicant
Hengstler, Jan G.
)
Characterizing the role of WISP1 in liver pathophysiology
(Applicant
Hengstler, Jan G.
)
Developmental consequences of prenatal exposure to endocrine disruptor chemicals - An investigation of epigenetic mechanisms in the Duisburg Birth Cohort Study
(Applicants
Kumsta, Robert
;
Schölmerich, Axel
)
Die Bedeutung von WISP1 für Leberregeneration, Proliferation und Überleben von Hepatozyten
(Applicant
Godoy, Patricio
)
Differenzierungspotential spezifischer Zelltypen der Leber: neue Wege der Leberregeneration
(Applicant
Hengstler, Jan G.
)
Klinische Prognosen auf Grundlage von genregulatorischen Netzwerken
(Applicant
Rahnenführer, Jörg
)
Konditionale Expression der Rezeptortyrosinkinase HER-2: Bedeutung für die Tumorentwicklung
(Applicant
Hengstler, Jan G.
)
NAFLD-NASH-HCC progression: mechanisms of stage-transitions and identification of time windows for prevention
(Applicant
Ghallab, Ahmed
)
Role of the interleukin-15/macrophage axis in the immune response of liver fibrosis
(Applicant
Hengstler, Jan G.
)
The role of conventional and liver resident NK cells in drug-induced liver injury and in the regulation of ILC2 cells
(Applicants
Hengstler, Jan G.
;
Watzl, Carsten
)
The role of the adhesion molecule L1CAM in the epithelial-mesenchymal transition (EMT) and metastasis of pancreatic ductal adenocarcinoma
(Applicant
Sebens, Susanne
)
Verbesserte prognostische Signaturen aus Microarray-Studien durch Auswahl von Genen mit charakteristischen Verteilungen
(Applicant
Rahnenführer, Jörg
)
Research Units
Completed projects
Dynamics of the vacuolar proteome of Arabidopsis thaliana in response to abiotic stress factors
(Applicant
Reinders, Jörg
)
Collaborative Research Centres
Completed projects
Mutations of the peroxisomal Fanconi-associated protein (FAP) as a cause for hereditary tubulopathy
(Project Heads
Reichold, Markus
;
Reinders, Jörg
;
Warth, Richard
)
Resistenzmechanismen von Tumoren gegenüber antineoplastischen Agenzien und ihre Regulation zum Therapieerfolg
(Project Head
Hengstler, Jan G.
)
Clinical Research Units
Completed projects
Development and application of analytical methods for metabolic cell analysis under patho-physiological conditions
(Applicants
Dettmer-Wilde, Katja
;
Gronwald, Wolfram
;
Oefner, Peter
;
Spang, Rainer
)
Proteomics and functional analysis of glucocorticoid-induced apoptosis of lymphoblastic leukemia cells under simultaneous administration of 2-deoxy-D-glucose
(Applicant
Oefner, Peter
)
Research Training Groups
Current projects
GRK 2624: Biostatistical methods for high-dimensional data in toxicology
(Spokesperson
Rahnenführer, Jörg
)
Completed projects
GRK 1427: Food Constituents as Triggers of Nuclear Receptor-mediated Intestinal Signalling
(Spokespersons
Esser, Charlotte
;
Proksch, Peter
)
Additional Information
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