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Institution
Klinikum der Universität München
Medizinische Klinik und Poliklinik IV
Address
Ziemssenstraße 1
80336 München
Deutschland
GERiT
This institution in GERiT
80336 München
Projects
Research Grants
Current projects
Anti-oxidative and immunoregulatory functions of uric acid in chronic kidney disease
(Applicant
Steiger, Stefanie
)
Cell type-specific functions of HMGB1 in necroinflammation of the kidney
(Applicant
Anders, Hans-Joachim
)
CKD combination therapy beyond dual RAS/SGLT2 inhibition
(Applicant
Anders, Hans-Joachim
)
Molecular mechanisms of tumorigenesis in primary aldosteronism
(Applicants
Reincke, Martin
;
Williams, Ph.D., Tracy Ann
)
Pathophysiology of hypercortisolism-associated myopathy
(Applicants
Halle, Martin
;
Reincke, Martin
;
Schoser, Benedikt
)
Role of steroid hormone differentiation during adolescence in metabolism and cardiometabolic health
(Applicants
Harris, Carla
;
Standl, Ph.D., Marie
)
Tubular regeneration and renal cell carcinoma following kidney transplantation - pathomechanisms
(Applicants
Anders, Hans-Joachim
;
Andrassy, Joachim
)
Completed projects
ACTH-Rezeptor-Expression und ACTH-Sensitivität: Charakterisierung der adrenalen Rezeptorregulation
(Applicant
Reincke, Martin
)
At the interface between endoplasmic reticulum and mitochondria: inhibition of SOAT1 as new treatment strategy against adrenocortical carcinoma
(Applicants
Fassnacht, Martin
;
Kroiß, Ph.D., Matthias
)
Bedeutung der TNF-Rezeptoren bei der Glomerulonephritis: Charakterisierung einer TNF-Rezeptor 2-Blockade als therapeutische Strategie bei Lupusnephritis
(Applicant
Vielhauer, Volker
)
Blocking regulatory T cell-attracting chemokines as therapeutic goal for the treatment of HCC
(Applicant
Anz, David
)
Bronchiale Kontraktion und Ca2+ -Signaling glatter Muskelzellen der Luftwege in Lungenschnitten
(Applicant
Bergner, Albrecht
)
Clinic and molekular defect in the hyper-IgE-Syndrome
(Applicant
Grimbacher, Bodo
)
Der thyreoide Natrium/Iodid-Symporter als neues therapeutisches Gen bei der Therapie des metastasierenden Prostatakarzinoms
(Applicant
Spitzweg, Christine
)
Die Rolle des chemokin-bindenden Proteins DARC bei Nierenerkrankungen
(Applicant
Segerer, Stephan
)
Funktionelle Charakterisierung neu identifizierter Gene mit Einfluss auf das Renin-Angiotensin-Aldosteron System
(Applicant
Reincke, Martin
)
GEnetic and mechanistic studies of primary Aldosteronism
(Applicants
Beuschlein, Felix
;
Reincke, Martin
;
Strom, Tim-Matthias
)
Hyperuricemia and crystal-induced nephropathies
(Applicant
Steiger, Stefanie
)
Immune-regulatory functions of atypical chemokine receptors in inflammatory renal diseases - Fibrosis-limiting role of ACKR2
(Applicant
Vielhauer, Volker
)
Inflammasome components NLRP3/ASC in epithelial cells and resident dendritic cells of the kidney
(Applicant
Anders, Hans-Joachim
)
Interleukin-1 Rezeptor-assoziierte Kinase (IRAK)-3 bei der Lupusnephritis
(Applicant
Anders, Hans-Joachim
)
Interleukin-22 in kidney regeneration
(Applicant
Anders, Hans-Joachim
)
MDM-2 in glomerular and interstitial kidney disease
(Applicants
Anders, Hans-Joachim
;
Thomasova, Ph.D., Dana
)
Molecular mechanisms of cholesterol embolism
(Applicant
Anders, Hans-Joachim
)
NALP3 Inflammasom bei renaler Entzündung
(Applicant
Anders, Hans-Joachim
)
Necroinflammation, kidney regeneration, and long term outcomes of acute tubular necrosis
(Applicant
Anders, Hans-Joachim
)
Pathophysiology Crystal-induced kidney injury
(Applicant
Anders, Hans-Joachim
)
PTX3 in renal Inflammation and Regeneration
(Applicant
Anders, Hans-Joachim
)
The role of CCL22 chemokine expression in the maintenance of immune homeostasis
(Applicant
Anz, David
)
Toll-like Rezeptoren bei infektiösen und nicht-infektiösen Nierenerkrankungen
(Applicant
Anders, Hans-Joachim
)
Typ I Interferon als Mediator der Glomerulonephritis
(Applicant
Anders, Hans-Joachim
)
Untersuchungen von immunologischen und viralen Faktoren, die zum Verlust der Kontrolle der Virämie durch CD8-T-Zellantworten in der chronischen HIV-Infektion führen
(Applicant
Draenert, Rika
)
Untersuchungen zum in vivo Stoffwechsel ungesättigter Fettsäuren mit stabilen Isotopen
(Applicant
Koletzko, Berthold V.
)
Zelluläre und molekulare Mechanismen des chronisch-auf-akuten Nierenversagens
(Applicant
Lech, Ph.D., Maciej
)
Zur immunstimulatorischen Funktion endogener Nukleinsäuren bei Initiation und Progression der Immunkomplex-Glomerulonephritis
(Applicant
Anders, Hans-Joachim
)
Research Fellowships
Completed projects
Adipose tissue type 2 immunity at perivascular niches
(Applicant
Sbierski-Kind, Julia
)
Double minute Chromosomen in der Krebstherapie: Die Mikronukleation von Resistenzgenen als Angriffspunkt für neue spezifische Therapiestrategien in der Behandlung solider Tumore
(Applicant
Astner, Sabrina
)
Pathogenetische Rolle von gamma, delta T-Lymphozyten bei Glomerulonephritis, interstitieller Nephritis und renaler Fibrose
(Applicant
Vielhauer, Volker
)
The role of granzymes in modulating target cell phagocytosis and immunogenicity
(Applicant
Hoves, Sabine
)
Untersuchung der humanen zellulären Immunantwort auf regulatorische und akzessorische HIV-1-Proteine während der akuten HIV-Infektion
(Applicant
Draenert, Rika
)
Research Units
Current projects
CoSiMed – Facilitating collaborative diagnostic competences in the collaboration of physicians: Effects of adapting scaffolds to the professional knowledge base of collaboration partners
(Applicants
Fischer, Martin R.
;
Fischer, Frank
)
FOR 2385: Facilitation of Diagnostic Competences in Simulation-Based Learning Environments in Higher Education
(Spokesperson
Fischer, Frank
)
HyperICU. Effect of muscle wasting on global metabolite release and glucose homeostasis in patients with sarcopenia and critical illness
(Applicants
Blobner, Manfred
;
Wackerhage, Henning
)
Visit-Math 2 – Fostering diagnostic competencies of pre-service teachers: Individual learning potentials throughout their course of studies and adaptation effects of prompts as scaffolds
(Applicant
Seidel, Tina
)
Completed projects
Transgenic strategies to overcome cellular rejection of pig-to-primate xenografts
(Applicants
Seissler, Jochen
;
Wolf, Eckhard
)
Untersuchung der Wirksamkeit alternativer Radionuklide (211At, 188Re), im Vergleich zu 131I nach Natrium/Iodid-Symporter-Gentransfer in extrathyreoidale Tumorzellen
(Applicant
Spitzweg, Christine
)
Heisenberg Professorships
Completed projects
Inflammation and nephron loss
(Applicant
Anders, Hans-Joachim
)
Heisenberg Grants
Completed projects
Inflammation and nephron loss
(Applicant
Anders, Hans-Joachim
)
Collaborative Research Centres
Completed projects
Einfluß der hochaktiven antiretroviralen Therapie auf die Regulation der Virusexpression im lymphatischen Gewebe
(Project Heads
Bogner, Johannes
;
Schatz, Octavian
;
Zietz, Christian
)
HIV-Enzephalopathie und Mikroangiopathie
(Project Head
Goebel, Frank-Detlef
)
Immunpathogenese der HIV-Infektion: pathogenetische Rolle von Aktivierungsmechanismen im lymphatischen Gewebe
(Project Head
Bogner, Johannes
)
Optimization and individualization of sodium iodide symporter (NIS)-based gene therapy in glioblastoma based on characterization of tumor heterogeneity and tumor micromilieus
(Project Head
Spitzweg, Christine
)
Pathogenese metabolischer Störungen als Folge der antiretroviralen Therapie
(Project Head
Goebel, Frank-Detlef
)
Regulation der Vermehrung von HIV über zelluläre Aktivierungsmechanismen im LTR
(Project Head
Bogner, Johannes
)
SFB 464: Pathogenese HIV-induzierter Erkrankungen
(Spokesperson
Goebel, Frank-Detlef
)
Zentrale Einrichtungen und Verwaltung
(Project Head
Goebel, Frank-Detlef
)
Priority Programmes
Completed projects
Plasma membrane-mediated non-genomic effects of T4, T3 and thyroid hormone metabolite tetrac on different aspects of mesenchymal stem cell biology and their signaling pathways
(Applicants
Nelson, Peter Jon
;
Spitzweg, Christine
)
CRC/Transregios
Current projects
Analytical platform
(Project Heads
Alves, Tiago
;
Bidlingmaier, Martin
;
Kurlbaum, Max
;
Peitzsch, Mirko
;
Walch, Axel Karl
)
Genetic and environmental contributors to vascular function in primary aldosteronism
(Project Heads
Fuß, Carmina Teresa
;
Hahner, Stefanie
;
Reincke, Martin
;
Schirbel, Andreas
)
Identification and functional characterisation of genetic contributors to primary aldosteronism
(Project Heads
Beuschlein, Felix
;
Gudermann, Thomas
;
Reincke, Martin
;
Schneider, Holger
)
Impact of CCR4 ligands on tissue Treg cells in islet autoimmunity
(Project Heads
Anz, David
;
Serr, Isabelle
)
Molecular pathology and treatment of Cushing’s disease
(Project Heads
Reincke, Martin
;
Theodoropoulou, Marily
)
Patient cohorts and biobanks
(Project Heads
Eisenhofer, Ph.D., Graeme
;
Fassnacht, Martin
;
Pamporaki, Ph.D., Christina
;
Reincke, Martin
)
Soluble and crystalline metabolites as modulators of neutrophil function
(Project Heads
Anders, Hans-Joachim
;
Steiger, Stefanie
)
Steroid hormones and cancer immunity – learning from adrenocortical carcinoma
(Project Heads
Fassnacht, Martin
;
Kroiß, Ph.D., Matthias
)
Targeting ferroptosis in adrenocortical carcinoma (ACC): from basic mechanisms to novel treatments
(Project Heads
Friedmann Angeli, José Pedro
;
Kroiß, Ph.D., Matthias
;
Weigand, Isabel
)
Completed projects
Treatment of type 1 diabetes with porcine islet cells: transplantation of multi-transgenic islets expressing immunomodulatory molecules
(Project Heads
Seissler, Jochen
;
Wolf-van Bürck, Lelia
)
Research Training Groups
Completed projects
GRK 438: Vascular Biology in Medicine
(Spokesperson
Siess, Wolfgang
)
GRK 1202: Oligonucleotides in Cell Biology and Therapy
(Spokesperson
Endres, Stefan
)
Additional Information
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