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Institution
Martin-Luther-Universität Halle-Wittenberg
Medizinische Fakultät
Institut für Molekulare Medizin
Address
Kurt-Mothes-Straße 3a
06120 Halle
Deutschland
GERiT
This institution in GERiT
06120 Halle
Projects
Research Grants
Current projects
Dual-targeting WEE1/AURK-A kinase proteolysis targeting chimera (PROTAC) for cancer therapy
(Applicants
Hüttelmaier, Stefan
;
Sippl, Wolfgang
)
Reverse engineering of the transcriptional network downstream of RAF/MAPK signaling
(Applicants
Blüthgen, Nils
;
Böttcher, Michael
)
Completed projects
Analyse von Spezifitäts- und Affinitätsdeterminanten der SH3 Domänen von Adapterproteinen der Crk-Familie
(Applicant
Feller, Ph.D., Stephan-Michael
)
Androgen-regulated microRNAs as relevant effectors of adipogenesis inhibition
(Applicant
Greither, Thomas
)
Das ß-Aktin Lokasom - Asymmetrische Proteinverteilung durch lokalisierte Translation
(Applicant
Hüttelmaier, Stefan
)
Defining genetic interactions and dependencies of microRNA biogenesis factors
(Applicant
Gutschner, Tony
)
Mechanismen der Signaltransduktion, Zelldifferenzierung und Zelltransformation durch das Adapterprotein Nck
(Applicant
Feller, Ph.D., Stephan-Michael
)
The control of mRNA fate during cellular stress
(Applicant
Hüttelmaier, Stefan
)
The Role of Plakophilin 1 in Inflammatory Signaling
(Applicant
Keil, René
)
The role of the RO60 (TROVE2) autoantigen in modulating cell-cycle progression, apoptosis and chemo-resistance in cancer cells
(Applicant
Hüttelmaier, Stefan
)
Topology and Grb2 interactions of the intrinsically disordered platform protein Gab1
(Applicants
Balbach, Jochen
;
Feller, Ph.D., Stephan-Michael
)
Research Units
Current projects
Coordination Funds
(Applicant
Hüttelmaier, Stefan
)
FOR 5433: RNA in focus (RIF): From mechanisms to novel therapeutic strategies in cancer treatment
(Spokesperson
Hüttelmaier, Stefan
)
Targeting oncofetal IGF2BP proteins by small molecule drugs in cancer
(Applicants
Balbach, Jochen
;
Hüttelmaier, Stefan
;
Sippl, Wolfgang
)
The role and target potential of IGF2BP1 in ovarian cancer progression and immune evasion
(Applicant
Bley, Nadine
)
The role and target potential of the RNA-binding protein MEX3A in lung adenocarcinoma
(Applicants
Hüttelmaier, Stefan
;
Sinz, Andrea
)
Completed projects
Asymmetric protein sorting via localizd translation - The role of ZBP protein in directing mRNA localization and translation
(Applicant
Hüttelmaier, Stefan
)
Priority Programmes
Completed projects
Control of mRNA-binding protein (mRBP) and mRNP function by Y RNAs
(Applicant
Hüttelmaier, Stefan
)
Collaborative Research Centres
Completed projects
Bedeutung mitochondrialer Phänotyp-Veränderungen im Myokard durch Fettzellhormone für Alters-assoziierte mitochondriale Funktionseinschränkungen
(Project Heads
Holtz, Jürgen
;
Rohrbach, Susanne
)
Functional domains and regulation of the oncofetal IMP proteins
(Project Head
Hüttelmaier, Stefan
)
Identifizierung von Signaltransduktionspartnern der Crk-Adapterproteinfamilie während der Differenzierung von hämatopoetischen Vorläuferzellen
(Project Head
Feller, Ph.D., Stephan-Michael
)
Veränderungen der mitochondrialen Transkription im Altersherzen als Primärmechanismus der Alterung
(Project Heads
Gellerich, Frank Norbert
;
Holtz, Jürgen
)
Major Research Instrumentation
Completed projects
Ultra-high content imaging (UCSI) for spatial biology applications
CRC/Transregios
Completed projects
Dehnungs-induzuierte Abschwächung der Wnt-Signalaktivität im Myokard: Bedeutung für kardiale Stammzellen, Kardiomyozyten und deren Interaktionen
(Project Heads
Guan, Kaomei
;
Hasenfuß, Gerd
;
Holtz, Jürgen
)
Research Training Groups
Current projects
GRK 2467: Intrinsically Disordered Proteins – Molecular Principles, Cellular Functions, and Diseases
(Spokesperson
Sinz, Andrea
)
GRK 2751: Inflammatory cues as modulators of early pancreatic carcinogenesis (InCuPanC)
(Spokesperson
Rosendahl, Jonas
)
Completed projects
GRK 1591: Posttranscriptional Control of Gene Expression: Mechanisms and Role in Pathogenesis
(Spokesperson
Hüttelmaier, Stefan
)
Additional Information
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