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Institution

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Universitätsklinikum Frankfurt
Klinik für Orthopädie (Friedrichsheim)

Address Marienburgstraße 2
60528 Frankfurt am Main
Deutschland

GERiT This institution in GERiT

60528 Frankfurt am Main

Projects

Priority Programmes
- Completed projects
  - Zur Kontrolle des Aktivitätszustandes von Mikrogliazellen: Intrinsische Modulation durch Astrozyten -extrinsische Deaktivierung durch Immunsuppressiva
    (Applicant Hailer, Nils )
Research Grants
- Current projects
  - Improving surgical treatment outcomes in Hip Osteoarthritis based on Biomechanical and BIomarker Discoveries (HOBBID)
    (Applicants van Drongelen, Ph.D., Stefan ; Sell, Stefan ; Stein, Thorsten )
- Completed projects
  - Role of perifibrillar proteins in collagen fibril assembly, fibril interactions and matrix remodelling
    (Applicant Zaucke, Frank )
  - Structure-function relationships in the collagen-specific chaperone Hsp47: Crystal structure, in-vivo and invitro studies and development of antifibrotic agents.
    (Applicant Baumann, Ulrich )
Research Units
- Current projects
  - Disease mechanisms and therapeutic interventions in non-classical osteogenesis imperfecta
    (Applicants Semler, Jörg Oliver ; Zaucke, Frank )
  - FOR 2722: Novel molecular determinants for musculoskeletal extracellular matrix homeostasis – a systemic approach (M2)
    (Spokesperson Brachvogel, Bent )
Collaborative Research Centres
- Completed projects
  - Structure-function relationships of Hsp47/SERPINH1 and its role in skin fibrosis
    (Project Heads Baumann, Ulrich ; Sengle, Gerhard ; Zaucke, Frank )

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