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Institution
Universitätsklinikum Aachen, AÖR
Klinik für Kardiologie, Angiologie und
Internistische Intensivmedizin (Med. Klinik I)
Address
Pauwelsstraße 30
52074 Aachen
Deutschland
GERiT
This institution in GERiT
52074 Aachen
Projects
Research Grants
Current projects
CeramStent2: novel ceramic-metal coatings for coronary implants to reduce local thrombotic events and to improve the hemocompatible behavior, mechanical stability and chemical long-time resistance
(Applicants
Neuss-Stein, Sabine
;
Schickle, Karolina
;
Vogt, Felix
)
Cytoskeleton Dynamics and Extracellular Vesicles in Vascular Calcification
(Applicant
Göttsch, Ph.D., Claudia
)
Development of individualized treatment strategies for titin-based dilated cardiomyopathy
(Applicants
Gramlich, Michael
;
Just, Steffen
)
Magnetic nanoparticles in a non-woven composite for therapy of paravalvular leakage in transcatheter heart valve replacement (TAVR-MADEN)
(Applicants
Jansen, Sebastian
;
Slabu, Ioana
;
Vogt, Felix
)
Regulation and functional relevance of GLP-2 in sepsis
(Applicant
Lehrke, Michael
)
Completed projects
An alternative pathway for hypofibrinolysis in type 2 diabetes: The role of complement C3
(Applicant
Schütt, Katharina
)
Analyse der Pathomechanismen für Titin-basierte dilatative Kardiomyopathie anhand eines transgenen Tiermodells
(Applicant
Gramlich, Michael
)
Drug-eluting coronary stents in stenosed arteries: medical investigation and computational modelling
(Applicants
Behr, Ph.D., Marek
;
Reese, Stefanie
;
Vogt, Felix
)
Effect of aerobic exercise on dendritic cell function in allergic airway inflammation
(Applicant
Müller, Tobias
)
Hybride Bildgebung aus biplaner Koronarangiographie und 2D-Strain-Echokardiographie zur zielgerichteten intraprozeduralen Diagnose und Steuerung der interventionellen Revaskularisationstherapie
(Applicants
Becker, Michael
;
de la Fuente Klein, Matìas
)
Inflammationsinduzierte Dyslipoproteinämie unter besonderer Berücksichtigung des NF-kB Signalweges.
(Applicant
Lehrke, Michael
)
Involvement of P2R signalling in the pathogenesis of fibrotic lung diseases
(Applicant
Müller, Tobias
)
Kernspintomographische Steuerung und Überwachung intramyokardialer Injektionen am ischämisch geschädigten Herzen
(Applicant
Krombach, Gabriele A.
)
Osteoklasten-assoziierter Rezeptor (OSCAR) als Bindeglied zwischen oxidativem Stress und Gefäßkalzifizierung
(Applicant
Göttsch, Ph.D., Claudia
)
Redox signaling in vascular calcification - Dual role of NOX proteins
(Applicant
Göttsch, Ph.D., Claudia
)
Regulation der prokoagulatorischen Aktivität und Tissue Factor Expression in Monozyten durch Peroxisome proliferator-activated receptors (PPARs)
(Applicant
Marx, Nikolaus Albert Helmut
)
Untersuchungen zu den vasoprotektiven Eigenschaften von GLP-1
(Applicant
Lehrke, Michael
)
Wirkung von PPAR-Aktivatoren auf Plaquestabilität und die Aktivierung CD4-positiver Lymphozyten
(Applicant
Marx, Nikolaus Albert Helmut
)
Research Fellowships
Completed projects
Auswirkungen der PPARyS112D/-Mutation auf Glukosemetabolismus und Atherosklerose im Mäusemodell
(Applicant
Lehrke, Michael
)
Charakterisierung des bei der Proliferation und Spezifikation kardialer Progenitorzellen involvierten Nkx2-5/Bmp2/Smad1 Rückkopplungsmechanismus
(Applicant
Gramlich, Michael
)
The role of IL-3 in myocardial infarction
(Applicant
Kahles, Florian
)
Independent Junior Research Groups
Current projects
The role of gut immune cells as a novel therapeutical target for cardiovascular disease
(Applicant
Kahles, Florian
)
Collaborative Research Centres
Completed projects
Bedeutung von C-Peptid in der frühen Atherogenese
(Project Heads
Marx, Nikolaus Albert Helmut
;
Walcher, Daniel
)
Bedeutung von Liver-X-Receptors und Peroxisome proliferator-activated receptors für die Aktivierung humaner CD4-positiver Lymphozyten
(Project Head
Marx, Nikolaus Albert Helmut
)
Research Units
Completed projects
Chemokine und vaskuläre Adhäsionsmoleküle bei Ischämie / Reperfusion und Myokardinfarkt: Rolle von erythrozytärem NO
(Applicant
Merx, Marc
)
Differenzielle Funktion von monozytärer Subpopulationen in kardiometabolischen Erkrankungen
(Applicant
Hristov, Mihail
)
CRC/Transregios
Current projects
CKD and coagulation: dysregulation of the alternative complement pathway
(Project Head
Schütt, Katharina
)
Enhanced thrombotic risk and myocardial dysfunction of the infarcted heart in CKD
(Project Heads
Marx, Nikolaus Albert Helmut
;
Noels, Ph.D., Heidi
)
Immune cell-lipid interaction, a mechanism of CKD-induced vascular complications
(Project Heads
Kahles, Florian
;
van der Vorst, Emiel
)
Integrated Research Training Group: Cardiovascular complications in CKD
(Project Heads
Göttsch, Ph.D., Claudia
;
Jankowski, Joachim
;
Niemeyer, Ph.D., Barbara Anne
)
Modulatory effects of SGLT2 inhibition on cardiac metabolism in CKD patients
(Project Heads
Lehrke, Michael
;
Marx, Nikolaus Albert Helmut
)
The role of post-translational modifications of sortilin receptors in CKD
(Project Head
Göttsch, Ph.D., Claudia
)
Completed projects
Micro functionalized shape memory implants
(Project Heads
Barcikowski, Stephan
;
Blindt, Rüdiger
;
Herzog, Dirk
;
Kracht, Dietmar
;
Ostendorf, Andreas
)
Priority Programmes
Current projects
In-stent restenosis in coronary arteries – computational and data-driven investigations towards translational modeling
(Applicants
Behr, Ph.D., Marek
;
Linka, Kevin
;
Vogt, Felix
)
Research Training Groups
Completed projects
GRK 460: Diagnostic and Therapeutic Concepts in Molecular Medicine
(Spokesperson
Lehmann-Horn, Frank
)
Additional Information
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