SFB 414:  Information Technology in Medicine - Computer and Sensor-Aided Surgery

• Subject Area: Medicine
• Term: from 1996 to 2007
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5480208

The collaborative research centre 414 is a joint venture of the University of Karlsruhe (TH), the University of Heidelberg and the German Cancer Research Centre (Deutsches Krebsforschungszentrum DKFZ) in order to explore computer-integrated methods to assist surgeons, and to make these methods available for clinical use. In pilot projects in the fields of heart surgery and cranio-maxillofacial surgery problem solutions and prototype systems are worked out. Research is focused upon concrete surgical issues. Primary goals of the computer-assisted surgery are more efficiency and economy, better quality and increased security of surgical interventions. Central aspects are image acquisition techniques and computer-assisted operation planning. In the current third period so-called connecting projects (Querschnittsprojekte) aim at a further development and improvement of methods and tools for modelling, segmentation, visualisation and quality assurance for surgical interventions in heart and head surgery. These methods are intended to be exemplarily applied in head and heart surgery. They will be evaluated by demonstrators for bone repositioning surgeries (head) and soft tissue surgeries (heart), cadaver and clinical experiments. Aim of the head projects in the third period is the further development of the surgical robot system, operation planning and control system, augmented reality based on projector and head-mounted displays in order to create a demonstrator comprising essential aspects and methods of sensor- and computer-assisted surgery. An intensive evaluation will follow. In the third period, the heart projects aim at enhancing the available methods and models developed in the second period and testing their manipulation in the clinical routine. This comprises operation planning and therapy control with 3D/4D functional image acquisition, perfusion contractility relationship, heart-lung machine as autonomous intelligent system, electrophysiological and morphological remodelling of the heart ventricles and the computer-assisted reconstruction of coronary vessels.

• DFG Programme: Collaborative Research Centres

Completed projects

• A - Allgemeine Infrastruktur, Datensicherheit und Kommunikation (Project Heads Düber, Christoph ;  Mühling, Joachim ;  Wörn, Heinz )
• H01 - Klinische Applikation und Entwicklung dreidimensionaler Verfahren: Unterstützung der Diagnostik und Therapie (Project Heads Hagl, Siegfried ;  Meinzer, Hans-Peter ;  de Simone, Raffaele ;  Wolf, Ivo )
• H2 - Ventrikulo-arterielle-Kopplung im kleinen Kreislauf (Project Head Szabó, Ph.D., Gábor )
• H3 - Automatisierung der Herz-Lungen-Maschine (Project Heads Hagl, Siegfried ;  Kiencke, Uwe )
• H4 - Rechnergestützte Planung, Simulation und Validierung herzchirurgischer Eingriffe (Project Heads Dössel, Olaf ;  Osswald, Brigitte R. )
• H5 - Rechnergestützte chrirugische Rekonstruktion von Herzklappen und der großen herznahen Gefäße (Project Heads Beller, Carsten ;  Dillmann, Rüdiger ;  Hagl, Siegfried )
• K1 - Operationsplanung und -steuerung in der Chirurgie (Project Heads Mühling, Joachim ;  Raczkowsky, Jörg ;  Wörn, Heinz )
• K2 - Navigation (Project Head Kiencke, Uwe )
• K3 - Roboterunterstützter Operationsarbeitsplatz (Project Heads Hassfeld, Stefan ;  Mühling, Joachim ;  Wörn, Heinz )
• K4 - Erweiterte Realität in der Chirurgie (Project Heads Dillmann, Rüdiger ;  Marmulla, Rüdiger ;  Wörn, Heinz )
• Q1 - Aufbereitung medizinischer Bilddaten: Diagnoseunterstützung (Project Heads Hassfeld, Stefan ;  Mende, Ulrich ;  Raczkowsky, Jörg ;  Wörn, Heinz )
• Q2 - Methodenevaluierung (Project Heads Hassfeld, Stefan ;  Szabó, Ph.D., Gábor )
• Q3 - Optimierung und Weiterentwicklung der 3D-Segmentierung sowie Integration in eine Open-Source Plattform zur Veröffentlichung der innerhalb des SFB erarbeiteten Erkenntnisse (Project Heads Meinzer, Hans-Peter ;  Wolf, Ivo )
• Q4 - Modellierung von Gewebestrukturen zur Darstellung operativer Veränderungen (Project Head Dillmann, Rüdiger )
• Q5 - Ein graphisches Simulationssystem für chirurgische Eingriffe (Project Head Dillmann, Rüdiger )
• Q6 - Datenschutz und Systemsicherheit für die medizinische Informationsverarbeitung (Project Heads Beth, Thomas ;  Georgi, Max Armin ;  Walz, Michael )

• Applicant Institution: Karlsruher Institut für Technologie (KIT) ; Campus Süd (aufgelöst)
• Participating University: Ruprecht-Karls-Universität Heidelberg
• Spokespersons: Professor Dr. Joachim Mühling, until 6/2006 (†); Professor Dr.-Ing. Heinz Wörn