Longitudinal trajectories of brain changes as mediators of course of illness: intermittent sampling (A02)

• Subject Area: Biological Psychiatry
• Term: since 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 521379614

The project aims to understand the biopsychosocial mechanisms underlying disease trajectories in affective disorders. Utilizing data from DFG FOR and BMBF Early-BipoLife cohorts (n=4,105) as well as CRC/TRR 2-year follow-up data spanning in total 11 years, the project explores the association of brain structure and function with (i) past disease trajectories; (ii) prospective disease trajectories and symptom changes; (iii) early and late environmental risk and protective factors; (iv) biological; and (v) behavioral measures; along with (vi) treatment.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 393: Trajectories of Affective Disorders: Cognitive-emotional Mechanisms of Symptom Change
• Applicant Institution: Philipps-Universität Marburg
• Project Heads: Professor Dr. Udo Dannlowski; Professor Dr. Tilo Kircher; Privatdozentin Dr. Eva Mennigen