The neural code of stimulus-triggered territorial aggression (A01)

• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: since 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 512007073

In the project a unique experimental model will be used to study the neurobiological basis of aggressive animal behavior and translate novel findings about its cellular and circuit underpinnings into human phenotypes of pathological aggression. Specifically, the post-weaning social isolation model of early-life adverse experience allows experimental access to dissect the 'switch' from functional adaptive aggression to excessive pathological aggressive behavior. The project addresses the principles that govern aggression-promoting information transfer along the AOB-to-MeA signaling pathway.

• DFG Programme: CRC/Transregios
• Subproject of: TRR 379: Neuropsychobiology of Aggression: A Transdiagnostic Approach in Mental Disorders
• Applicant Institution: Rheinisch-Westfälische Technische Hochschule Aachen
• Project Head: Professor Dr. Marc Spehr