Impact of natural LPR1 proteoforms on Fe-dependent phosphate sensing (C03)

• Subject Area: Plant Biochemistry and Biophysics ; Plant Physiology ; Plant Cell and Developmental Biology
• Term: since 2024
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 514901783

C03 explores the interplay between phosphate and iron availability in root system architecture. LOW PHOSPHATE ROOT 1 (LPR1), a cell wall-localised multicopper oxidase, facilitates iron-dependent phosphate sensing, influencing root meristem activity and overall architecture. Various LPR1 proteoforms will be expressed, biochemically characterised, and structurally analysed in the Stubbs lab. In planta studies will investigate their functional consequences under different growth/soil conditions. This project provides insights into nutrient-dependent root responses.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1664: Plant Proteoform Diversity - SNP2Prot
• Applicant Institution: Martin-Luther-Universität Halle-Wittenberg
• Project Heads: Professor Dr. Steffen Abel; Dr. Christin Naumann; Professor Dr. Milton T. Stubbs