Der Lebenszyklus ausgewählter Staphylococcus aureus Phagen, dessen Beeinflussung durch infektions-relevante Stimuli und die damit verbundene Modulation des Virulenzpotentials von S. aureus

• Applicant: Professorin Dr. Christiane Wolz
• Subject Area: Parasitology and Biology of Tropical Infectious Disease Pathogens
• Term: from 2005 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5440595

• Final Report Year: 2011

Final Report Abstract

No abstract available

Publications

• 2006. Extensive phage dynamics in Staphylococcus aureus contributes to adaptation to the human host during infection. Mol Microbiol 61:1673-85
  Goerke, C., C. Wirtz, U. Fluckiger, and C. Wolz
  
• 2007. High phenotypic diversity in infecting but not in colonizing Staphylococcus aureus populations. Environ Microbiol 9:3134-3142
  Goerke, C.; M. Gressinger; K. Endler; C. Breitkopf; K. Wardecki; M. Stern M.; C. Wolz; Kahl, B.C.
  
• 2009. Diversity of prophages in dominant Staphylococcus aureus clonal lineages. J Bacteriol 191:3462-3468
  Goerke, C., R. Pantucek, S. Holtfreter, B. Schulte, M. Zink, D. Grumann, B. M. Broker, J. Doskar, and C. Wolz
  
• 2009. Transcription of the phage-encoded Panton-Valentine leukocidin of Staphylococcus aureus is dependent on the phage lifecycle and on the host background. Microbiology 155:3491-9
  Wirtz, C., W. Witte, C. Wolz, and C. Goerke
  
• 2010. Insertion of host DNA into PVL- encoding phages of the Staphylococcus aureus lineage ST80 by intra-chromosomal. Virology 406:322-327
  Wirtz, C., W. Witte, C. Wolz, and C. Goerke
  
• 2010. Multilocus PCR typing strategy for differentiation of Staphylococcus aureus siphoviruses reflecting their modular genome structure. Environ Microbiol 12:2527-2538
  Kahankova, J., R. Pantucek, C. Goerke, V. Ruzickova, P. Holochova, and J. Doskar
  
• 2010. Recurrent furunculosis - associations with Panton-Valentine leukocidin and the genetic background of Staphylococcus aureus. J Clin Microbiol 48:1527-1535
  Masiuk, H., K. Kopron, D. Grumann, C. Goerke, J. Kolata, J. Jursa-Kulesza, S. Giedrys-Kalemba, B. M. Broker, and S. Holtfreter