Glutamate receptor field dynamics

• Applicant: Professor Dr. Stephan J. Sigrist
• Subject Area: Molecular Biology and Physiology of Neurons and Glial Cells
• Term: from 2004 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5439152

• Final Report Year: 2009

Final Report Abstract

No abstract available

Publications

• A Glutamate-Receptor-lnteracting-Protein Homologue organizes muscle guidance in Drosophila. Genes & Development 18, 223-237 (2004)
  Swan L., Wichmann C., Prange U., Schmid A., Schmidt M., Schwarz T., Ponimaskin E., Madeo F., Vorbrüggen G., and Sigrist S.J.
  
• Chronological aging leads to apoptosis in yeast. J. Cell Biol. 16, 501-7 (2004)
  Herker E., Jungwirth H., Lehmann KA., Maldener C., Fröhlich KU., Wissing S., Buttner S., Fehr M., Sigrist S.J., and Madeo F.
  
• Four different subunits are essential for expressing the synaptic glutamate receptor at neuromuscular junctions of Drosophila. J. Neurosci. 25, 3209-3218 (2005)
  Qin G., Schwarz T., Kittel R. J., Schmid A., Rasse T. M., Kappei D., Ponimaskin E., Heckmann M., and Sigrist S.J.
  
• Glutamate receptor dynamics organising synapse formation in vivo. Nat Neurosci. 8, 898 - 905 (2005)
  Rasse T., Fouquet W., Schmid A., Kittel R., Mertel S., Sigrist B., Schmidt, Merino C., Qin G., Quentin C., Madeo F., Heckmann M., and Sigrist S.J.
  
• The 4.1 protein coracle mediates subunit-selective anchoring of Drosophila glutamate receptors to the postsynaptic actin cytoskeleton. J. Neurosci. 25, 6667-75 (2005)
  Chen K., Merino C, Sigrist S.J., and Featherstone D.
  
• Bruchpilot, a protein with homology to ELKS/CAST/ERC, is required for structural integrity and function of synaptic active zones in Drosophila. Neuron 49, 833-844 (2006)
  Wagh D., Rasse M., Asan E., Hofbauer A., Schwenkert I. , Dürrbeck H., Buchner S., Qin G., Wichmann C., Kittel R., Sigrist S.J., and Buchner E.
  
• Echinoid and Drosophila GRIP organize Drosophila muscle guidance via a complex Interaction. EMBO J . 25, 3640-51 (2006)
  Swan L.E., Schmidt M., Schwarz T., Ponimaskin E., Prange U., Boeckers T., Thomas U., and Sigrist S.J.
  
• Non-NMDA type glutamate receptors are essential for maturation but not for initial assembly of synapses at Drosophila NMJs. J . Neurosci. 26, 11267-11277 (2006)
  Schmid A., Qin G., Wichmann C., Kittel R., Mertel S., Fouquet W., Schmidt M., Heckmann M., and Sigrist S.J.
  
• Nuclear trafficking of Drosophila Frizzled-2 during synapse development requires the PDZ protein dGRlP. PNAS 103, 7841-6 (2006)
  Ataman B., Ashley J., Gorczyca D., Gorczyca M., Mathew D., Wichmann C., Sigrist S.J., and Budnik V.
  
• The Drosophila Bruchpilot protein is needed for presynaptic active zone assembly and calcium channel clustering to ensure efficient, fast neurotransmission. Science 312, 1051-1054 (2006)
  Kittel R., Wichmann C., Rasse T., Fouquet W., Schmid A., Wagh D., Buchner E., Heckmann M., and Sigrist S.J.
  
• Endonuclease G regulates yeast life and death. Mol. Cell 9, 911-917 (2007)
  Büttner S., Carmona-Gutierrez D., Wissing S., Eisenberg T., Sigrist C., Ruli D., Knauer H., Beranek A. , Kollroser M., Fröhlich K., Sigrist S.J., and Madeo F.
  
• Live imaging of synapse development and measuring protein dynamics using two-color fluorescence recovery after photo-bleaching at Drosophila synapses. Nature Protocols 2, 3285-3298 (2007)
  Fuger P., Behrends L. B., Mertel S., Sigrist S. J., and Rasse T. M.
  
• The Ig CAM Basigin controls distribution and release of synaptic vesicles at Drosophila neuromuscular junctions. J. Cell Biology 177, 843 (2007)
  Besse F., Mertel S., Kittel R., Wichmann C., Rasse T., Sigrist S.J., and Ephrussi A.
  
• Activity-dependent site-specific changes of glutamate receptor composition in vivo. Nature Neuroscience 11, 659- 666 (2008)
  Schmid A., Hallermann S., Kittel R.J., Khorramshahi O., Frölich A., Quentin C , Rasse T., Mertel S., Heckmann M., and Sigrist S.J.
  
• Rapid activity-dependent modifications in synaptic structure and function require bidirectional Wnt signaling. Neuron 57, 705-718 (2008)
  Ataman B., Ashley J., Gorczyca M., Ramachandran P., Fouquet W., Sigrist S. J., and Budnik V.