Rolle des Zink-Finger Proteins Gfi1B in der normalen Hämato- und Lymphopoese und seine funktionelle Redundanz zu Gfi1

• Applicant: Professor Dr. Tarik Möröy
• Subject Area: Cell Biology
• Term: from 2004 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5417434

• Final Report Year: 2009

Final Report Abstract

No abstract available

Publications

• Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Res. 2005, Feb 17;33(3):987-98
  Vassen L, Fiolka K, Mahlmann S and Möröy T
  
• Gfi1 and Gfi1b act equivalently in hematopoiesis but have distinct, non-overlapping functions in inner ear development. EMBO Reports, 2006, Mar;7(3):326-33
  Fiolka K, Hertzano R, Vassen L, Zeng H, Hermesh O, Avraham KB, Dührsen U and Möröy T
  
• Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromation EMBO Journal, 2006, Jun 7;25(11):2409-19
  Vassen L, Fiolka K and Möröy T
  
• Gfi1b:Green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood, 2007, Mar 15;109(6):2356-64
  Vassen L, Okayama T and Möröy T