Untersuchung von positiver und negativer Selektion im Thymus nach induzierter T-Zellrezeptor-Expression

• Applicant: Professor Dr. Thorsten Buch
• Subject Area: Cell Biology
• Term: from 2003 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5406169

• Final Report Year: 2010

Final Report Abstract

No abstract available

Publications

• A Cre-Inducible Toxin Receptor Mediates Cell Lineage Ablation Following Diphtheria Toxin Administration, Nature Methods 2005; 2:419-426
  Buch, T., Heinen, T.J.A.J., Tertilt, C., Kremer, M., Heppner, F.L., Wunderlich, F.T., Jung, S., Waisman, A.
  
• Agouti-related peptide-expressing neurons are mandatory for feeding Nature Neuroscience 2005 Oct;8(10):1289-91
  Gropp, E, Gao, Q., Xu, A., Janoschek, R., Buch, T., Plum, L., Waisman, A., Barsh, G., Horvath, T.L., Brüning, J.
  
• DNA Vaccines: Methods and Protocols, „Protection from Autoimmunity by DNA Vaccination Against T Cell Receptor (TCR)“ Methods Mol Med. 2006;127:269-80
  Thorsten Buch and Ari Waisman
  
• Reconstitution of thymic positive selection rescues T helper cell dependent immune responses in murine MHC class II deficiency, Blood. 2006 Feb 15;107(4):1434-44
  Buch, T., Polic, B., Clausen, B., Alferink, J., Weiss, S., Chang, C.-H., Flavell, R. Jonjic, S., Förster, I.
  
• Rescue of thymic development by abTCR in pTa deficient mice depends on the presence of the positively selecting restriction element, Eur. J. Immunol. 2008 Feb;38(2):391-9
  Croxford, A., Rieux-Laucat, F., Förster, I., Waisman, A. Buch, T.
  
• Encyclopedia of Molecular Mechanisms of Disease. “MHC class II deficiency” Springer Press 2009
  Thorsten Buch, Ansgar Schulz, and Irmgard Förster