On the role of AP-2 transcription-factors: Molecular and developmental biological experiments

• Applicant: Professor Dr. Hubert Schorle
• Subject Area: Pathology
• Term: from 2002 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5390987

• Final Report Year: 2009

Final Report Abstract

No abstract available

Publications

• 2006. Diagnostic value of markers M2A, OCT3/4, AP-2gamma, PLAP and c-KIT in the detection of extragonadal seminomas. Histopathology 49:290-7
  Biermann, K., D. Klingmuller, A. Koch, T. Pietsch, H. Schorle, R. Buttner, and H. Zhou
  
• [Embryonal germ cells and germ cell tumors] Verh Dtsch Ges Pathol. 2007;91:39-48
  Biermann K, Heukamp LC, Nettersheim D, Steger K, Zhou H, Franke FE, Guetgemann I, Sonnack V, Brehm R, Berg J, Bastian PJ, Müller SC, Wang-Eckert L, Schorle H, Büttner R
  
• [On the role of transcription factor family AP-2 for development and disease-lessons from mouse models] Verh Dtsch Ges Pathol. 2007;91:91- 7
  Schorle H.
  
• c-KIT isfrequently mutated in bilateral germ cell tumours and down-regulated during progression from intratubular germ cell neoplasia to seminoma. J Pathol. 2007 Sep 3
  Biermann, K., Goke, F., Nettersheim, D., Eckert, D., Zhou, H., Geshaw, l.,Schorle, H. and Buettner, R.
  
• Gene expression profiling identifies new biological markers of neoplastic germ cells. Anticancer Res. 2007 Sep-Oct;27 (5A):3091- 100
  Biermann K, Goke F, Nettersheim D, Eckert D, Zhou H, Kahl P, Gashaw I, Schorle H, Buttner R
  
• TCam-2 but not JKT-1 cells resemble seminoma in cell culture. Cell Tissue Res. 2007 Nov 15
  Eckert D, Nettersheim D, Heukamp LC,Kitazawa S, Biermann K, Schorle H
  
• Expression of BLIMP1/PRMT5 and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors. BMC Developmental Biology 2008, Nov 7;8{1):106
  Dawid Eckert, Katharina Biermann, Daniel Nettersheim, Ad J.M. Gillis, Klaus Steger, Hans-Martin Jäck, Annette M. Müller, Leendert H.J. Looljenga and Hubert Schorle