Molekularbiologische Charakterisierung von Parkin: physiologische Funktion und pathologische Veränderungen beim juvenilen Parkinson-Syndrom

• Applicant: Professor Dr. Thomas Gasser
• Subject Area: Clinical Neurology; Neurosurgery and Neuroradiology
• Term: from 2000 to 2004
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5235050

• Final Report Year: 2007

Final Report Abstract

No abstract available

Publications

• Complex relationship between Parkin mutations and Parkinson disease. Am. J. Med. Genet. 2002;114(5):584-591
  West A, Periquet M, Lincoln S, Lucking CB, Nicholl D, Bonifati V, et al.
  
• How much phenotypic variation can be attributed to parkin genotype? Ann. Neurol. 2003;54(2):176-185
  Lohmann E, Periquet M, Bonifati V, Wood NW, De Michele G, Bonnet AM, et al.
  
• Parkin interacts with the proteasome subunit alpha4. FEBS Lett 2005;579(18):3913-9
  Dachsel JC, Lucking CB, Deeg S, Schultz E, Lalowski M, Casademunt E, et al.
  
• Parkin modulates gene expression in control and ceramide-treated PC12 cells. Mol Biol Rep 2006;33(1):13-32
  Unschuld PC, Dachsel J, Darios F, Kohlmann A, Casademunt E, Lehmann-Horn K, et al.