Steuerung und Katalyse der chemischen Verknüpfung von PNA-Konjugaten durch Oligonucleotid-Template

• Applicant: Professor Dr. Oliver Seitz
• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: from 1999 to 2009
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5202102

• Final Report Year: 2008

Final Report Abstract

No abstract available

Publications

• "New isocysteine building blocks and chemoselective peptide ligation". Org. Biomol. Chem. 2004, 2, 59-65
  C. Dose, O. Seitz
  
• "Single Nucleotide Specific PNA-Peptide Ligation on Synthetic and PCR DNA Templates". J. Am. Chem. Soc. 2004, 126, 9970-9981
  S. Ficht, A. Mattes, O. Seitz
  
• "As Fast and Selective as Enzymatic Ligations: Unpaired Nucleobases Increase the Selectivity of DNA-Controlied Native Chemical PNA-Ligation". ChemBioChem. 2005, 6, 2098 - 2103
  S. Ficht, C. Dose, O. Seitz
  
• "Convergent Synthesis of Peptide Nucleic Acids by Native Chemical Ligation". Org. Lett. 2005, 7, 4365 - 4368
  C. Dose, O. Seitz
  
• "Reducing Product Inhibition in DNA-Template Controlled Ligation Reactions". Angew. Chem. Int. Ed 2006, 45, 5369-5373
  C. Dose, S. Ficht, O. Seitz