Nicht-hämodynamische Mechanismen von Angiotensin II bei der Progression von Nierenerkrankungen

• Applicant: Professor Dr. Gunter Burkhard Wolf
• Subject Area: Nephrology
• Term: from 1991 to 2010
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 5129104

• Final Report Year: 2009

Final Report Abstract

No abstract available

Publications

• Angiotensin II induces hypoxiainducible factor-1a in PC 12 cells through a posttranscriptional mechanism: Role of AT2- receptors. Am J Nephrol 24, 415-421 (2004)
  G.Wolf, R.Schroeder, R.A.K.Stahl
  
• Angiotensin II upregulates Toll-like receptor 4 on mesangial cells. J Am Soc Nephrol 17, 1585-1693 (2006)
  G.Wolf, J.Bohlender, T.Bondeva, T.Roger, F.Thaiss, U.Wenzel
  
• The novel WD-repeat protein Morg1 acts as a molecular scaffold for HIF prolyl-hydroxylase 3 (PHD3). J Biol Chem 281, 8645-8655 (2006)
  U.Hopfer, H.Hopfer, K.Jablonski, R.A.K.Stahl, G.Wolf
  
• Differenfial regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on API and PU.1 transcriptional sites. Am J Nephrol 27, 308-314 (2007)
  T.Bondeva, T.Roger, G.Wolf
  
• Morg1 heterozygous mice are protected from acute renat ischemia/reperfusion injury
  E.Hammerschmidt, I.Loeffler, G.Wolf
  
• Reduced Morg1 expression in ischemic human brain. Neuroscien Lett 2009
  D.Haase, S.Keiner, C.Mawrin, G.Wolf