Project Details
Projekt
Probing multiprotein assemblies with native mass spectrometry (P13)
Subject Area
Biochemistry
Term
since 2022
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 450648163
Mitochondrial ATPases are of high relevance for (human) life. In project P13, we will probe changes in the ATP synthase complex formation in correlation to mutations causing neuropathological diseases by native mass spectrometry. In addition, we want to investigate different mechanistic principles, which control recruitment of specific phospholipids or lipopolysaccharides. To advance these aims, we will push boundaries regarding the use of membrane mimics for native mass spectrometry.
DFG Programme
Collaborative Research Centres
Applicant Institution
Goethe-Universität Frankfurt am Main
Project Head
Professorin Dr. Nina Morgner
