Regulation of potassium channel YugO in bacterial electrical signaling (P04)

• Subject Area: Biochemistry
• Term: since 2022
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 450648163

In biofilms, bacteria use electrical signaling for cell-cell communication. In Bacillus subtilis, potassium channel YugO is suggested to be a key player by mediating potassium efflux at nitrogen starvation. In project P04, we will elucidate the molecular principles of electrical signaling by structurally and functionally characterizing YugO and identifying the network required for activation.

• DFG Programme: Collaborative Research Centres
• Subproject of: SFB 1507: Protein Assemblies and Machineries in Cell Membranes
• Applicant Institution: Goethe-Universität Frankfurt am Main
• Project Head: Professorin Dr. Inga Hänelt