Tuning Radical Reactivity in Photocatalytic Transformations of NHC-Activated Substrates (B05)

• Subject Area: Organic Molecular Chemistry - Synthesis and Characterisation
• Term: since 2021
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 444632635

The project B5 aims to harness the unique ability of N-heterocyclic carbenes (NHCs) to stabilize adjacent radical centers (carbon, oxygen: part A; boron: part B) for synthetic applications i.a. cyclisation cascades). The visible light induced formation of the radical centers will take place only after successful assembly of the according NHC-substrate adducts and their reactivity will be modulated by secondary interactions in the binary or ternary complexes. Supporting in-depth mechanistic investigations will make use of time-resolved spectroscopy on various time-scales and sophisticated computations (MDs, electronic structure calculations).

• DFG Programme: CRC/Transregios
• Subproject of: TRR 325: Assembly Controlled Chemical Photocatalysis
• Applicant Institution: Technische Universität München (TUM)
• Project Head: Professorin Dr. Julia Rehbein