Confocal Laser Scanning Microscope (CLSM)

• Subject Area: Plant Sciences
• Term: Funded in 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 446988475

In 2007, the Department of Biology of the Philipps-University Marburg founded the Center of Advanced Light Microscopy (CALM) as a subsistent and subsidiary facility, which is classified as a Major Research Instrumentation unit of the Philipps-University. The two confocal microscopes of the CALM are intensively being used by 10 groups of the department biology and research involving these CLSM devices has led to more than 50, in part high-ranked, publications in the past five years.Several new faculty have been hired at the Department of Biology in the last two years, with the applicants Großhans (October 2019), Helker (October 2018) and Voll (October 2017) being three PIs with a considerable demand for confocal imaging machine time. This increases the current estimate for overall CLSM time at the department to about 7000 hours per year. The research focus of many groups at the department relies on CLSM-based structural and functional analysis of processes on the organellar, cellular and tissue level. Technological progress in the field of confocal laser scanning microscopy (CLSM) now offers applications with improved temporal, spatial and spectral resolution, which provides additional arguments for operating modern CLSM devices at the CALM in order to foster state-of-the-art research at the Department of Biology.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: Konfokales Laser-Scanning-Mikroskop (KLSM)
• Instrumentation Group: 5090 Spezialmikroskope
• Applicant Institution: Philipps-Universität Marburg
• Leader: Professor Dr. Lars Voll