Replacement purchase for a 800 MHz NMR spectrometer

• Subject Area: Biological Chemistry and Food Chemistry
• Term: Funded in 2020
• Project identifier: Deutsche Forschungsgemeinschaft (DFG) - Project number 441546624

The research groups at the BNMRZ employ NMR spectroscopy to obtain molecular and mechanistic insight for essential biological processes that underlie physiological and diseaselinked cellular processes. The application involves an 800 MHz NMR spectrometer which will be employed for solution-state as well as MAS solid-state NMR. Research topics involve the analysis of protein structure and dynamics of amyloid fibrils, membrane proteins and virus assemblies. In solution, membrane protein nanodisc assemblies, protein-RNA and proteinchaperone complexes are investigated. An additional focus area is the development of methods for solution-state and MAS solid-state NMR.

• DFG Programme: Major Research Instrumentation
• Major Instrumentation: 800 MHz NMR-Spektrometer (Teilfinanzierung)
• Instrumentation Group: 1740 Hochauflösende NMR-Spektrometer
• Applicant Institution: Technische Universität München (TUM)
• Leader: Professor Dr. Bernd Reif