Project Details
Projekt
Computational Optimization of Piezoelectric Scaffolds for Bone Regeneration (COPs)
Subject Area
Biomaterials
Orthopaedics, Traumatology, Reconstructive Surgery
Orthopaedics, Traumatology, Reconstructive Surgery
Term
from 2020 to 2024
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Project number 435260927
The aim of this study is to investigate the role of piezoelectricity on scaffold supported bone regeneration. Our long-term goal is to use this understanding for the design optimization of piezoelectric scaffolds to treat large bone defects. We aim to employ mathematical and computational techniques to determine locally the mechanical and electrical signals generated due to the physiological stimulation of a piezoelectric scaffold and to investigate how these signals influence the bone regeneration process. We will investigate how different parameters such as applied deformation, electric field (voltage), frequency, duration of stimulation etc. will influence the bone healing process.
DFG Programme
Research Grants
Co-Investigators
Dr.-Ing. Dragan Marinkovic; Dr.-Ing. Melika Mohammadkhah, Ph.D.
