Characterization of the endoplasmic reticulum stress response in the intestinal epithelium under conditions of chronic inflammation: impact of innate and adaptive immune signals

Applicant Professor Dr. Dirk Haller

Subject Area Public Health, Healthcare Research, Social and Occupational Medicine

Term from 2007 to 2011

Project identifier Deutsche Forschungsgemeinschaft (DFG) - Project number 43209635

Final Report Year 2010

Final Report Abstract

No abstract available

Loss of Toll-like receptor 2 and 4 leads to differential Induction of endoplasmic reticulum stress and proapoptotic responses In the intestinal epithelium under conditions of chronic inflammation. J. Proteome. Res. 2009;8(10):4406-17
Messlik A, Schmechel S, Kisling S, Bereswill S, Heimesaat MM, Fischer A, Göbel U, Haller D
Depletion of dietary Iron alters the gut microbiome and prevents Crohn's disease ileitis. Gut 2010 Nov 26 (Epub ahead of print)
Werner T, Wagner S. Martinez I, Walter J, Chang JS, Clavel T, Kisling S, Schuemann K, Haller D